I-15-Chwetheza i-HR-HPV ehlonweyo - ichonga ubukho kunye nomsebenzi we-HR-HPV

Umhlaza womlomo wesibeleko, eyona nto iphambili yokufa phakathi kwabasetyhini kwihlabathi liphela, kubangelwa kukusuleleka kwe-HPV. I-OnCogenic inokwenzeka yosulelo lwe-HR-HPV luxhomekeke kumagama anyukayo yemfuza ye-E6 kunye ne-E7. Iprotheyini ye-E6 kunye ne-E7 ibotshwe kwi-proproins Proupersor Proupersor Proupersor Proupersor Proupersor Proupers

Nangona kunjalo, uvavanyo lwe-HPv DNA luqinisekisa ubukho bentsholongwane, awuqondi phakathi kokufumana usulelo kunye nosulelo olusebenzayo. Ngokwahlukileyo, ukufunyanwa kwe-HPV E6 / E7 Recripts isebenza njengendawo ethile ye-biramarker yentetho ye-chiccogene esebenzayo ye-intcopical neoplasia (i-cin) okanye i-carcinoma echanekileyo.

I-HPV E6 / E7 MRNAUkuvavanywa kunika izibonelelo ezibalulekileyo kubuNikelo lomhlaza wesibeleko:

• Uvavanyo loMngcipheko oluchanileyo: Chonga usulelo olusebenzayo lwe-HPV, ukubonelela ngovavanyo lomngcipheko oluchanekileyo ngakumbi kuvavanyo lwe-HPV.
• I-Triegi efanelekileyo: Izikhokelo zekhokheli ekuchongeni izigulana ezifuna uphando oluthe kratya, ukunciphisa iinkqubo ezingeyomfuneko.
• Isixhobo esinokubakho sokuhlolwa: Inokusebenza njengesixhobo sovavanyo lwexesha elizayo kwixa elizayo, ngakumbi ukuba ibe yimingcipheko enkulu.
• Iindidi ezili-15 ze-papillomavirus emngciphekweni omkhulu we-E6 / E7 Gener gene (Fluorescence PCR) ukusuka kwi #MMT, isixhobo esisebenzayo se-HRV, sisixhobo esisebenzayo se-HPV kwaye / okanye ulawulo lwesigulana.

Iimpawu zemveliso:

• Ukugubungela ngokupheleleyo: Ii-15 hr-hpv zihambelana nomhlaza womlomo wesibeleko ezigutyungelwe;
• Imvakalelo elungileyo: 500 iikopi / ml;
• Ubukhulu becala: Akukho msebenzi wenqamlezo nge-cytomegalovirus, HSV II kunye neDNA yeMithombo yeMithombo yoBuntu;
• Iindleko ezisebenzayo: Iithagethi zokuvavanya zinxulumana ngokusondeleyo nesifo esinokwenzeka, ukunciphisa iimviwo ezingafunekiyo ngeendleko ezongezelelweyo;
• Ukuchaneka okugqibeleleyo: i-IC kuyo yonke inkqubo;
• Ukuhambelana ngokubanzi: Ngenkqubo ye-PCR ye-PCR PCR;