Izisombululo ezipheleleyo zokufumanisa iDengue ngokuchanekileyo – ii-NAAT kunye nee-RDT

Imingeni

Ngenxa yemvula eninzi, usulelo lwe-dengue lunyuke kakhulu kutshanje kumazwe amaninzi ukusuka eMzantsi Melika, eMzantsi-mpuma Asia, eAfrika ukuya kuMzantsi Pasifiki. I-dengue iye yaba yingxaki ekhulayo yezempilo yoluntu malunga4 abantu abazibhiliyoni kumazwe ali-130 abasengozini yokosuleleka.

Ukuba banentsholongwane, izigulane ziya kuba neengxakiumkhuhlane ophezulu, ukurhawuzelela, intloko ebuhlungu, intlungu emva kwamehlo, iintlungu zemisipha, iintlungu zamalungu, isicaphucaphu, urhudo, ukuhlanza kunye nentlungu yesisu, kwaye usenokuba sengozini yokufa.

ZethuIsisombululos

I-immunoimmune ekhawulezayo kwaye imolekyuli Izixhobo zovavanyo lwe-dengue ezivela kwi-Macro kunye ne-Micro-Test zivumela ukuxilongwa kwe-dengue ngokuchanekileyo kwiimeko ezahlukeneyo, zincedangexesha elifanelekileyo kwayeiyasebenzazonyangounyango.

Ukhetho 1 lweDengue: Ukufunyanwa kweNucleic Acid

Intsholongwane yeDengue I/II/III/IV NIkhithi yokuFumanisa i-ucleic Acid- ulwelo/i-lyophilized

Ukufunyanwa kwe-Dengue nucleic acid kuchonga into ethileezineii-serotypes, ezivumela ukuxilongwa kwangethuba, ulawulo olufanelekileyo lwezigulane, kunye nokuphuculwa kokujonga izifo kunye nokulawula ukuqhambuka kwazo.

• Ugutyungelwe ngokupheleleyo: Ii-serotypes zeDengue I/II/III/IV zigutyungelwe;
• Isampuli Elula: I-Serum;
• Ukwandisa okufutshane: imizuzu engama-45 kuphela;
• Uvakalelo oluphezulu: iikopi ezingama-500/mL;
• Ixesha elide lokugcinwa kwesilwanyana: iinyanga ezili-12;
• UkulungelaInguqulelo ye-Lyophilized (i-premixed liquid tech) yenza kube lula ukuhamba komsebenzi kwaye kube lula ukugcina nokuthutha;
• Ukuhambelana okubanzi: Kuhambelana kakhulu nezixhobo ze-PCR eziphambili ezithengiswayo; kunye ne-MMT's Inkqubo yokuFumanisa iiMolekyuli ngokuzenzekelayo ye-AIO800

Jonga i-AIO 800

Ukusebenza okuthembekileyo

	I-DENV I	I-DENV II	I-DENV III	I-DENV IV
Uvelwano	100%	100%	100%	100%
Ukuchaneka	100%	100%	100%	100%

Ukuhamba komsebenzi

Ukhetho 2 lweDengue: Ukufunyanwa Okukhawulezileyo

I-Dengue NS1 Antigen, IgM/IgG AntibodyIsixhobo sokuFumanisa esiBini;

Thisikhempu yedengueouvavanyo lubona i-antigen ye-NS1 ukuze kufunyanwe isifo kwangethuba kunye ne-IgM&ii-antibodies ze-IgGthatha isigqiboeyokuqalaorusulelo lwesibini kwaye luqinisekisa i-dengueusulelo, ukubonelelauvavanyo olukhawulezileyo nolupheleleyo lwemeko yokosulelwa yidengue.

• Ukhuseleko lwexesha elizeleyo: Zombini i-antigen kunye ne-antibody zifunyenwe ukuba zigubungele lonke ixesha losulelo;
• Ezinye iindlela zokukhetha imizekelo:I-serum/plasma/igazi elipheleleyo/igazi elisencamini yomnwe;
• Isiphumo esiKhawulezayo: Imizuzu eli-15 kuphela;
• Ukusebenza okulula:Akukho sixhobo somculo;
• Ukusetyenziswa Okubanzi: Iimeko ezahlukeneyo ezifana nezibhedlele, iikliniki, kunye namaziko empilo oluntu, okuphucula ukufikeleleka kokuxilongwa.

Ukusebenza okuthembekileyo

	I-NS 1 Ag	IgG	I-IgM
Uvelwano	99.02%	99.18%	99.35%
Ukuchaneka	99.57%	99.65%	99.89%

Ikhithi yokuFumanisa iZika Virus IgM/IgG Antibody;

I-Dengue NS1 AntigenIkhithi yokuFumanisa;

Ikhithi yokuFumanisa i-Antibody ye-Dengue Virus IgM/IgG