Yintoni ebangela usulelo C. Diff?
Usulelo lwe-C.Diff lubangelwa yintsholongwane eyaziwa ngokuba yintsholongwaneI-Clostridioides difficile (C. difficile), edla ngokuhlala ngokungenabungozi emathunjini. Noko ke, xa ulungelelwaniso lwebhaktiriya emathunjini luphazamisekile, ngokufuthi ukusetyenziswa kwamayeza okubulala iintsholongwane abanzi, iC. difficile inokukhula ngokugqithisileyo ize ivelise ityhefu, ekhokelela kusulelo.
Le bhaktiriya ikhona kuzo zombiniityhefukunye neefom ze-non-toxigenic, kodwa kuphela iintlobo ze-toxigenic (i-toxins A kunye ne-B) ezibangela izifo. Babangela ukuvuvukala ngokuphazamisa iiseli ze-epithelial zamathumbu. I-Toxin A ngokuyintloko yi-enterotoxin eyonakalisa i-gut lining, inyusa ukungena, kunye nokutsala iiseli zomzimba ezikhupha iicytokines ezivuthayo. I-Toxin B, i-cytotoxin enamandla ngakumbi, ijolise kwi-actin cytoskeleton yeeseli, ekhokelela ekujikelezeni kweeseli, ukuhlukana, kunye nokufa kweeseli. Ngokudibeneyo, ezi zityhefu zibangela umonakalo wezicubu kunye nokuphendula okunamandla kokuzivikela komzimba, okubonakaliswa njenge-colitis, isifo sohudo, kwaye kwiimeko ezinzima, i-pseudomembranous colitis-ukuvuvukala okukhulu kwekholoni.
Ingaba kwenzeka njaniC. Diffusasazeko?
C.Diff isasazeka ngokulula. Ikhona kwizibhedlele, ezihlala zifumaneka kwii-ICU, ezandleni zabasebenzi basesibhedlele, kwimigangatho yesibhedlele kunye ne-handrails, kwii-thermometers ze-elektroniki, kunye nezinye izixhobo zonyango ...
Imiba yoMngcipheko weC. Diff Usulelo
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●Ukulaliswa esibhedlele ixesha elide; -
●Unyango lwe-Antimicrobial; -
●Iiarhente zeChemotherapy; -
●Utyando lwakutsha nje (imikhono yesisu, i-gastric bypass, utyando lwekholoni); -
●Isondlo se-naso-gastric; -
●Ngaphambili C. diff usulelo;
Iimpawu ze C. Diff usulelo
C. usulelo lwe diff lunokungakhululeki kakhulu. Uninzi lwabantu lurhudo oluqhubekayo kunye nokungakhululeki kwisisu. Ezona mpawu zixhaphakileyo zezi: urhudo, isisu esibuhlungu, isicaphucaphu, ukuphelelwa ngumdla wokutya, ifiva.
Njengoko usulelo lwe-C. diff lusiya lusiba lubi kakhulu, kuya kubakho ukuvela kohlobo oluntsokothileyo lwe-C. diff eyaziwa ngokuba yi-colitis, i-pseudomembranous enteritis kunye nokufa.
Uxilongoof C. Diff Usulelo
INkcubeko yeBhaktheriya:I-Sensitive kodwa ichitha ixesha (i-2-5days), ayikwazi ukwahlula iintlobo ze-toxigenic kunye ne-non-toxigenic;
Inkcubeko yeToxin:ichonga iintlobo ze-toxigenic ezibangela izifo kodwa zichitha ixesha (i-3-5days) kwaye zincinci;
Ukufunyanwa kwe-GDH:ngokukhawuleza (i-1-2hrs) kunye neendleko ezisebenzayo, ezinochuku kakhulu kodwa azikwazi ukwahlula iintlobo ze-toxigenic kunye ne-non-toxigenic;
Uvavanyo lwe-Cell Cytotoxicity Neutralization Assay (CCNA):ibhaqa i-toxin A kunye ne-B enovakalelo oluphezulu kodwa itya ixesha (iintsuku ezi-2-3), kwaye ifuna izibonelelo ezikhethekileyo kunye nabasebenzi abaqeqeshiweyo;
Ityhefu A/B ELISA: Uvavanyo olulula kunye nolukhawulezayo (i-1-2hrs) kunye novakalelo oluphantsi kunye nokungahambi kakuhle kobuxoki rhoqo;
Iimvavanyo zeNucleic Acid Amplification (NAATs): Ngokukhawuleza (1-3hrs) kunye novakalelo oluphezulu & oluthe ngqo, ukufumanisa imfuza enoxanduva lokuvelisa i-toxin;
Ukongezelela, iimvavanyo zemifanekiso yokuhlola amathumbu, njenge-CT scan kunye ne-X-reyi, zisenokusetyenziswa ukunceda ekuxilongeni i-C. diff kunye neengxaki ze-C. diff, ezifana ne-colitis.
Unyango lwe C. Diff usulelo
Iinketho ezininzi zonyango ziyafumanekaC. diff usulelo. Apha ngezantsi kukho ukhetho olungcono:
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●Amayeza okubulala iintsholongwane ngomlomo afana nevancomycin, i-metronidazole okanye i-fidaxomicin aqhele ukusetyenziswa njengoko iyeza linokudlula kwindlela yokwetyisa lize lifike kwikholoni apho kuhlala khona i-C. diff bacteria. -
●I-Intravenous metronidazole ingasetyenziselwa unyango ukuba usulelo lwe-C. diff lumandundu. -
●Ufakelo lwe-fecal microbiota lubonise ukusebenza kakuhle ekunyangeni izifo rhoqo ze-C. diff kunye ne-C. diff eyingozi kakhulu yosulelo olungaphenduliyo kwii-antibiotics. -
●Utyando lunokuba yimfuneko kwiimeko ezinzima.
Isisombululo soxilongo esivela kwi-MMT
Ukuphendula imfuno yokukhangela ngokukhawuleza, ngokuchanekileyo ukufumanisa i-C. difficile, sazisa i-Nucleic Acid Detection Kit yethu entsha ye-Clostridium difficile toxin A / B gene, ukuxhobisa abaqeqeshi bezempilo ukuba benze ukuxilongwa kwangaphambili kunye ngokuchanekileyo kunye nokuxhasa umlo wokulwa nosulelo olufunyenwe esibhedlele.
●Uvakalelo oluPhezulu: Ibona phantsi njenge200 CFU/mL,;
●UkuJonga okuchanekileyo: Ichaza ngokuchanekileyo i-C. difficile toxin A / B gene, ukunciphisa iimpawu zobuxoki;
●Ukufunyanwa kwePathogen ngokuthe ngqo: Isebenzisa uvavanyo lwe-nucleic acid ukuchonga ngokuthe ngqo iijene ze-toxin, ukuseka umgangatho wegolide woxilongo.
●Ihambelana ngokupheleleyo neizixhobo zePCR eziphambili ezijongana neelebhu ezininzi;
Isampulu-kwiMpenduloIsisombululo kwiMacro & Micro-Test's AIO800 Mobile PCR Lab
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●Isampula-ukuphendula i-Automation - Layisha iityhubhu zesampulu zangaphambili (1.5-12 mL) ngokuthe ngqo, ukuphelisa i-pipetting manual. Ukutsalwa, ukukhulisa, kunye nokufumanisa kuzenzekelayo ngokupheleleyo, ukunciphisa izandla ngexesha kunye nephutha lomntu. -
●Ukukhuselwa koNgcono lweNqanaba elisibhozo-Ukuhamba komoya okukhokelwayo, uxinzelelo olubi, ukuhluzwa kwe-HEPA, ukunyanyiswa kwe-UV, ukusabela okutywiniweyo, kunye nezinye izikhuselo ezidibeneyo zikhusela abasebenzi kunye nokuqinisekisa iziphumo ezithembekileyo ngexesha lovavanyo oluphezulu.
Ukufumana iinkcukacha ezithe vetshe:
https://www.mmtest.com/nucleic-acid-detection-kit-for-clostridium-difficile-toxin-ab-gene-fluorescence-pcr-product/
Contact us to learn more: marketing@mmtest.com;
Ixesha lokuposa: Aug-12-2025