I-Fungus exhaphakileyo, eyona nto ibangela i-Vaginitis kunye ne-Lung fungal Infections-Candida Albicans

Ukubaluleka kokuFumana

I-Fungal candidiasis (ekwabizwa ngokuba yi-candid infection) ixhaphake kakhulu. Kukho iintlobo ezininzi zeCandida kwayengaphezu 200 iintlobo Candida ibeifunyenwe ukuza kuthi ga ngoku.Candida albicans (CA) yeyona pathojeni, ebalelwayo malunga ne-70% yazo zonke izifo zeklinikhi.I-CA, ekwaziwa ngokuba yiCandida emhlophe, idla ngokuba yiparasitizes kwiinwebu zolusu lomntu, umlomo womlomo, umjelo wesisu, ubufazi, njl.A UCanzibe kubangela usulelo lwenkqubo, usulelo lobufazi, usulelo olusezantsi lwendlela yokuphefumla, njl.

I-Vaginitis:Malunga ne-75% yabasetyhini bafumana i-vulvovaginal candidiasis (VVC) ubuncinane kanye kanye ebomini babo, kwaye isiqingatha sabo siya kuphinda sibuyele. Ukongeza kwiimpawu ezibuhlungu zomzimba ezifana nokurhawuzelelwa kwe-vulvovaginal kunye nokutshisa, iimeko ezinzima zinokubangela ukungazinzi, okucaca ngakumbi ebusuku, kwaye kuchaphazela ngokunzulu iimvakalelo zesigulana kunye nengqondo. I-VVC ayinayo imbonakalo yeklinikhi ethile, kwaye iimvavanyo zasebhubhoratri zingundoqo wokuxilongwa.

Usulelo lomngundo emiphungeni:CA usulelo ngunobangela obalulekileyo wokusweleka ngenxa yokosulela esibhedlele kwaye ithatha malunga nama-40% aIzigulana ezigula kakhulu kwi-ICU. Uphando lwe-multicenter retrospective survey of pulmonary fungal disease e-China ukusuka kwi-1998 ukuya kwi-2007 yafumanisa ukuba i-pulmonary candidiasis ibalwa kwi-34.2%, aphoCA Ibalelwa kwi-65% ye-pulmonary candidiasis. Indawo yokuphefumla CA Usulelo alunazo iimpawu zeklinikhi eziqhelekileyo kwaye lunento ethile ephantsi kwimbonakaliso yemifanekiso, lwenza ukuxilongwa kwangoko kube nzima. Imvumelwano yengcali malunga noxilongo kunye nonyango lwesifo sokungunda kwemiphunga icebisa ukuba kusetyenziswe iisampulu zesikhohlela eziqeqeshwe ngokukhohlela nzulu, ukomeleza uvavanyo lwebhayoloji yemolekyuli, kunye nokubonelela ngezicwangciso zonyango lomngundo oluhambelanayo.

Iintlobo zeesampuli

 

Isisombululo sokuFumana

Iimpawu zemveliso

Ukusebenza kakuhle:I-Isothermal amplification yokwenza lula ukukhulisa kunye nesiphumo ngaphakathi kwe-30 min;

Iimpawu eziphezulu: Siprimer ecacileyo kunye neprobe (rProbe)yenzelwekwimimandla egcinwe kakhulu ye-CAkunye nenkqubo evaliweyo ngokupheleleyo ukubona ngokuthe ngqo i-CA DNA kwimizekelo.Akukho-cross-reactivity kunye nezinye izifo zentsholongwane ye-urogenital tract;

Uvakalelo oluphezulu: i-LoD ye-10² ibhaktheriya/mL;

I-QC esebenzayo: Isalathiso sangaphakathi sangaphandle sokulawula i-reagent kunye nomgangatho wokusebenza kunye nokuphepha ukungahambi kakuhle kobuxoki;

Iziphumo ezichanekileyo: 1,000 iimeko zeesenti ezininzir uvavanyo lwezonyango kunye aireyithi yokuthotyelwa iyonkeof 99.7%;

Ukugqunywa ngokubanzi kweeserotypes: Zonke iiserotypes zeCandida albicans A, B, Cigqunyiwe ngeiziphumo ezihambelanayoxa kuthelekiswa neubhaqo lolandelelwano;

Vula ii-reagents: Iyahambelana ne-PCR eqhelekileyo yangokusystems.

Ulwazi lweMveliso

Ikhowudi yeMveliso	Igama lemveliso	Inkcazo	Inombolo yesatifikethi.
HWTS-FG005	Ikhithi yokubona i-Nucleic Acid esekwe kwi-Enzymatic Probe Isothermal Amplification (EPIA) yeCandida Albicans	50 iimvavanyo/ikhithi
HWTS-EQ008	Easy AmpIxesha langempela leFluorescence Isothermal Detection System	HWTS-1600P 4 iziteshi ze-fluorescence	NMPA2023322059
HWTS-EQ009		HWTS-1600s 2iziteshi ze-fluorescence