I-Fungus Exhaphakileyo, Unobangela Oyintloko weVaginitis kunye nosulelo lwe-Lung Fungal - iCandida Albicans

Ukubaluleka koKuchongwa

I-fungus candidiasis (ekwaziwa ngokuba lusulelo lwe-candida) ixhaphakile. Kukho iintlobo ezininzi ze-Candida kwayeiintlobo ezingaphezu kwama-200 zeCandida ibeifunyenwe ukuza kuthi ga ngoku.IiCandida albicans (CA) yeyona nto ibangela izifo ezininzi, ezithi malunga ne-70% yazo zonke izifo zonyango.I-CA, ekwaziwa ngokuba yi-white Candida, idla ngokufunxa iintsholongwane kwi-mucous membranes yolusu lomntu, emlonyeni, kwindlela yokugaya ukutya, kwilungu lobufazi, njl. Xa umsebenzi womzimba womntu ungaqhelekanga okanye izityalo eziqhelekileyo zingalingani, i-CA UCanzibe kubangela usulelo oluhamba emzimbeni, usulelo lwangasese, usulelo olusezantsi kwindlela yokuphefumla, njl.

Ukuvuvukala kwamalungu esini:Malunga nama-75% abasetyhini bafumana i-vulvovaginal candidiasis (VVC) ubuncinane kanye ebomini babo, kwaye isiqingatha sabo siya kuphinda sibuye. Ukongeza kwiimpawu zomzimba ezibuhlungu ezifana nokurhawuzelelwa nokutsha kwe-vulvovaginal, iimeko ezinzima zinokubangela ukungazinzi, okubonakala ngakumbi ebusuku, kwaye kuchaphazela kakhulu iimvakalelo zesigulana kunye nengqondo yengqondo. I-VVC ayinazo iimpawu ezithile zeklinikhi, kwaye uvavanyo lwelabhoratri lubalulekile ekuxilongweni.

Usulelo lwefungus lwemiphunga:CA usulelo luyimbangela ebalulekileyo yokufa ngenxa yosulelo esibhedlele kwaye ixabisa malunga nama-40%izigulane ezigula kakhulu kwi-ICU. Uphando olujonga emva olujoliswe kwiindawo ezininzi lwesifo sefungus semiphunga eTshayina ukususela ngo-1998 ukuya ku-2007 lufumanise ukuba i-pulmonary candidiasis yayingama-34.2%, aphoCA zibalwa njenge-65% ye-pulmonary candidiasis.A Usulelo alunazo iimpawu eziqhelekileyo zeklinikhi kwaye alunazo iimpawu ezicacileyo kwimifanekiso, nto leyo eyenza kube nzima ukufumanisa isifo kwangethuba. Imvumelwano yeengcali malunga nokuxilongwa kunye nonyango lwesifo semiphunga icebisa ukusetyenziswa kweesampuli zesikhohlela ezifanelekileyo ezicocwe nzulu, ukuqinisa uvavanyo lwebhayoloji yemolekyuli, kunye nokubonelela ngezicwangciso zonyango lwemiphunga ezifanelekileyo.

Iintlobo zeSampulu

 

Isisombululo sokuFumanisa

Iimpawu zemveliso

Ukusebenza kakuhle：Ukwandiswa kwe-isothermal ukuze kwenziwe lula ukwandiswa, nto leyo ephumela kwimizuzu engama-30;

Ukucaciswa okuphezulu: Siprimer ecacileyo kunye neprobe (rProbe)yenzelwekwiindawo ezigcinwe kakuhle ze-CAenenkqubo evaliweyo ngokupheleleyo yokubona ngokukodwa i-CA DNA kwiisampuli. Akukho ntshukumo edibeneyo nezinye izifo ezibangelwa kusulelo lwendlela ye-urogenital;

Uvakalelo oluphezulu: I-LoD ye-10² iintsholongwane/mL;

I-QC esebenzayo: Isalathiso sangaphakathi sangaphandle kwi-reagent yolawulo kunye nomgangatho wokusebenza kwaye siphephe izinto ezingalunganga;

Iziphumo ezichanekileyo: Iimeko ezili-1,000 zezifo ezininziuvavanyo lweklinikhi oluneizinga elipheleleyo lokuthobela imithethoof 99.7%;

Ukugubungela ngokubanzi ii-serotypes: Zonke ii-serotypes ze-Candida albicans A, B, Cigutyungelwe kunyeiziphumo ezihambelanayoxa kuthelekiswa neukufunyanwa kokulandelelana;

Ii-reagents ezivulekileyo: Ziyahambelana ne-PCR eqhelekileyo yangokuii-systii-ems.

Ulwazi lweMveliso

Ikhowudi yeMveliso	Igama lemveliso	Inkcazo	Inombolo yeSatifikethi
I-HWTS-FG005	I-Nucleic Acid Detection Kit esekwe kwi-Enzymatic Probe Isothermal Amplification (EPIA) yeCandida Albicans	5Uvavanyo/ikhithi eyi-0
I-HWTS-EQ008	I-Amp elulaInkqubo yokuFumanisa i-Fluorescence Isothermal yexesha langempela	I-HWTS-1600P 4 imijelo ye-fluorescence	I-NMPA2023322059
I-HWTS-EQ009		Ii-HWTS-1600s 2imijelo ye-fluorescence