Ukufunyanwa ngaxeshanye kwesifo sephepha kunye ne-MDR-TB

Isifo sephepha (TB), nangona sinokuthintelwa kwaye sinokunyangeka, sisengumngcipheko kwimpilo yehlabathi. Abantu abaqikelelwa kwi-10.6 yezigidi bagula yi-TB ngo-2022, nto leyo ebangele ukufa kwabantu abaqikelelwa kwi-1.3 yezigidi kwihlabathi liphela, kude kakhulu nomlinganiselo we-2025 weSicwangciso sokuphelisa i-TB yi-WHO. Ngaphezu koko, ukunganyangeki ngamayeza okulwa ne-TB, ngakumbi i-MDR-TB (enganyangekiyo yi-RIF kunye ne-INH), kuya kuqhubeka nokuba nzima kunyango lwe-TB lwehlabathi kunye nokuthintela.

Ukuxilongwa okusebenzayo nokuchanekileyo kwesifo sephepha kunye nokuchasana namayeza e-TB YI-KEY kwimpumelelo yonyango kunye nokuthintela isifo sephepha.

Isisombululo Sethu

UMarco kunye novavanyo oluncinciUkufunyanwa kwe-TB ezi-3 kwi-1 zosulelo lwe-TB/i-RIF kunye ne-NIH ResistanceIsixhobo sokufumanisa sivumela ukuxilongwa ngokufanelekileyo kwe-TB kunye ne-RIF/INH kuvavanyo olunye ngetekhnoloji yeMelting curve.

Ukufunyanwa kwe-3-in-1 TB/MDR-TB okufumanisa usulelo lwe-TB kunye nokuxhathisa amayeza aphambili odidi lokuqala (RIF/INH) kwenza ukuba unyango lwe-TB lufike ngexesha kwaye luchaneke.

I-Mycobacterium Tuberculosis Nucleic Acid kunye neRifampicin, iKit yokuFumanisa ukuKhawuleza kwe-Isoniazid (iMelting Curve)

Ufezekisa ngempumelelo uvavanyo lwe-TB oluphindwe kathathu (usulelo lwe-TB, i-RIF kunye ne-NIH Resistance) ngexesha elinye lokufumanisa!

Isiphumo esikhawulezayo:Ifumaneka kwiiyure ezi-2-2.5 kunye nokutolikwa kweziphumo ngokuzenzekelayo okunciphisa uqeqesho lobugcisa lokusebenza;

Isampuli yoVavanyo:I-sputum, i-LJ Medium, i-MGIT Medium, i-Bronchial Lavage Fluid;

Uvakalelo oluphezulu:Iibhaktheriya ezili-110/mL zeTB, iibhaktheriya ezili-150/mL ze-RIF, iibhaktheriya ezingama-200/mL ze-INH, ukuqinisekisa ukubonwa okuthembekileyo nokuba imithwalo yebhaktheriya iphantsi.

Iithagethi ezininzi:I-TB-IS6110; I-RIF-resistance-rpoB (507~533); I-INH-resistance-InhA, AhpC, katG 315;

Ukuqinisekiswa koMgangatho:Ulawulo lwangaphakathi lokuqinisekisa umgangatho wesampulu ukunciphisa izinto ezingalunganga;

Ukuhambelana Okubanziy: Ukuhambelana neenkqubo ezininzi ze-PCR eziphambili ukuze kufikeleleke kwiilebhu ezininzi (SLAN-96P, BioRad CFX96);

Ukuthotyelwa kweMigaqo ye-WHO:Ukunamathela kwizikhokelo ze-WHO zolawulo lwesifo sephepha esinganyangekiyo ngamayeza, ukuqinisekisa ukuthembeka nokufaneleka kwindlela yokusebenza kwezonyango.