Hlalani Phambi Kokosuleleka kokuphefumla: I-Cutting-Edge Multiplex Diagnostics yezisombululo eziKhawulezayo nezichanekileyo.

Njengoko ixesha lasekwindla kunye nobusika lifika, lizisa ukwehla okubukhali kwamaqondo obushushu, singena kwixesha leziganeko eziphezulu zosulelo lokuphefumla-umngeni oqhubekayo nowoyikekayo kwimpilo yoluntu yehlabathi. Olu sulelo lusuka kwingqele exhaphakileyo ekhathaza abantwana abancinci ukuya kwinyumoniya eyingozi esongela ubomi babantu abadala, izibonakalisa njengenkxalabo yezempilo kwindawo yonke. Nangona kunjalo, isoyikiso sabo sokwenyani sikhulu kakhulu kunokuba uninzi lucinga: ngokutsho koMbutho wezeMpilo weHlabathi (i-WHO), usulelo olusezantsi lokuphefumla sesona sifo sibulalayo emhlabeni, sibanga ubomi obumalunga ne-2.5 yezigidi ngo-2021 kuphela kwaye sibekwe njengesihlanu kunobangela wokufa kwihlabathi jikelele. Xa sijamelene nesi sisongelo singabonakaliyo sempilo, sinokuhlala njani sihamba inyathelo elinye ngaphambili?

Iindlela zoThutho kunye namaQela asemngciphekweni omkhulu

Ii-RTIs zosulela kakhulu kwaye zisasazwa ikakhulu ngeendlela ezimbini eziphambili:

1. Ukuhanjiswa kweDroplet: Iintsholongwane zikhutshelwa emoyeni xa umntu osulelekileyo ekhohlela, ethimla, okanye ethetha. Umzekelo, ngexesha lokuhamba kukawonke-wonke, amathontsi athwele iintsholongwane ezinjengomkhuhlane anokosulela abantu abakufutshane.
2. Ugqithiso loQhagamshelwano: Iintsholongwane ezikwindawo engcolisekileyo zinokungena emzimbeni ngeenwebu zemifinya xa abantu bebamba umlomo, impumlo, okanye amehlo ngezandla ezingahlanjwanga.

Iimpawu eziqhelekileyoofIi-RTIs

Ii-RTIs zihlala zineempawu ezidlulanayo ezinjengokhohlokhohlo, umkhuhlane, umqala obuhlungu, impumlo evuzayo, ukudinwa, kunye nokuqaqamba komzimba, nto leyo eyenza kube nzima ukuchonga ngokuchanekileyo i-pathogen. Ukongeza, ii-RTI ziphawulwa:

1. Iintetho zeklinikhi ezifanayo: Iintsholongwane ezininzi zivelisa iimpawu ezifanayo, zinzima ukuhlukana phakathi kwentsholongwane, i-bacterial, kunye ne-mycoplasma.
2. Ugqithiso oluPhezulu: Ii-RTIs zisasazeka ngokukhawuleza, ngakumbi kwiindawo ezixineneyo, zigxininisa ukubaluleka kokuxilongwa kwangaphambili kunye ngokuchanekileyo ukulawula ukuqhambuka.
3. Usulelo kunye: Izigulane zinokuthi zisuleleke ngeentsholongwane ezininzi ngexesha elinye, ukwandisa umngcipheko weengxaki, okwenza ukuxilongwa kwe-multiplex kubaluleke kakhulu ekuxilongeni ngokuchanekileyo nangokucokisekileyo.
4. Ukunyuka kwamaxesha onyaka: I-RTIs ihlala i-spike ngamaxesha athile onyaka, igxininise izixhobo zokunakekelwa kwempilo kunye nokugxininisa imfuno yezixhobo ezifanelekileyo zokuxilonga ukulawula umthamo wezigulane ezongeziweyo.

Imingcipheko yoNyango lweemfama kwiIi-RTIs

Amayeza angaboniyo, okanye ukusetyenziswa ngokungakhethi konyango ngaphandle kokuxilongwa ngokufanelekileyo, kubangela imingcipheko emininzi:

• Masking Iimpawu: Amayeza anokwenza lula iimpawu ngaphandle kokujongana nonobangela, ukulibazisa unyango olufanelekileyo.
• Ukumelana neAntimicrobial Resistance (AMR): Ukusetyenziswa okungafunekiyo kwe-antibiotic kwi-RTIs yentsholongwane inegalelo kwi-AMR, inzima ukusuleleka kwikamva.
• Ukuphazamiseka kweMicroecology: Ukusetyenziswa kakubi kwamayeza kunokwenzakalisa iimicroorganisms zomzimba eziluncedo, ezikhokelela kusulelo lwesibini.
• Ukonakala kwelungu: Amayeza amaninzi anokonakalisa amalungu abalulekileyo njengesibindi nezintso.
• Iziphumo ezibi: Ukulibaziseka ukuchongwa kwe-pathogen kunokubangela iingxaki kunye nempilo embi, ngakumbi kumaqela asemngciphekweni.

Ukuxilongwa ngokuchanekileyo kunye nonyango olujoliswe kuyo lungundoqo kulawulo olusebenzayo lwe-RTI.

Ukubaluleka koFundo lwe-Multiplex ekuFundeni ii-RTIs

Ukufunyanwa kwe-multiplex ngaxeshanye kujongana nemiceli mngeni ebangelwa zii-RTIs kwaye ibonelela ngeenzuzo ezininzi ezibalulekileyo:

1. UkuPhuculwa kokuSebenza ngokuDidiya: Ngokuchonga ii-pathogens ezininzi kuvavanyo olulodwa, ukufunyanwa kwe-multiplex kunciphisa ixesha, izixhobo kunye neendleko ezinxulumene novavanyo olulandelelanayo.
2. Unyango oluchanekileyo: Ukuchongwa okuchanekileyo kwe-pathogen kwenza unyango olujoliswe kuyo, ukuphepha ukusetyenziswa okungafunekiyo kwe-antibiotics kunye nokunciphisa umngcipheko wokumelana ne-antimicrobial.
3. Iingxaki kunye nemingcipheko: Ukuxilongwa kwangaphambili kunye ngokuchanekileyo kunceda ukukhusela iingxaki ezinzima, ezifana ne-pneumonia okanye ukunyanzeliswa kwezifo ezingapheliyo, ngokuququzelela ukungenelela ngexesha elifanelekileyo.
4. Ukusasazwa koNonophelo lwezeMpilo: Izixhobo zokuxilonga ezisebenzayo zilungelelanisa ulawulo lwezigulane, ukunciphisa uxinzelelo kwiinkqubo zokhathalelo lwempilo ngexesha lonyaka okanye ubhubhane.
   
   Umbutho waseMelika weMicrobiology (ASM) uxoxa ngeenzuzo zeklinikhi zokuchongwa kweephaneli zemolekyuli ezininzingeibhaktheriya, intsholongwane, kunye ne-parasitic pathogens, ukunciphisa imfuno yovavanyo oluninzi kunye neesampuli. I-ASM igxininisa ukuba uvakalelo olwandisiweyo kunye nexesha elikhawulezayo lokuguqula olu vavanyo luvumela ukuxilongwa ngexesha elifanelekileyo kunye nokuchanekileyo, okubalulekileyo kukhathalelo olusebenzayo lwesigulane.Uvavanyo olukhulu kunye novavanyo oluncinci's Innovative Isisombululo kwi-Multiplex RTIs Ukufunyanwa

   Iindidi ezisibhozo zeeNxulumana zokuphefumla kwiNucleic Acid yeKitkwaye iEudemon AIO800ILebhu yePCR ephathwayozigqame ngokuchaneka kwazo, ukululakunye nempumeleloy.

   Iindidi ezisibhozo zeeNxulumana zokuphefumla kwiNucleic Acid yeKit

   -Thayipha I kwiiNkqubo zePCR eziqhelekileyo

   

   • Inkcazo ebanzi: Ngaxeshanye iyabhaqaintsholongwane yomkhuhlane A (IFV A), intsholongwane yomkhuhlane B (IFVB), ​​intsholongwane yokuphefumla i-syncytial virus (RSV), i-adenovirus (Adv), i-human metapneumovirus (hMPV), i-rhinovirus (Rhv), i-Parainfluenza virus (PIV) kunye ne-Mycoplasma pneumoniae (MP)in i-oropharyngeal/i-nasopharyngeal swabiisampulu.
   • Ukucacisa okuphezulu: Ugwema ukuxhamla kwi-cross-reactivity kunye nezinye iintsholongwane zokuphefumula, ukunciphisa ukuxilongwa kakubi.
   • Uvakalelo oluPhezulu: Ichonga nje abambalwaIikopi ze-200 / ml, okwenza ukuba i-pathogens ibonwe kwisigaba sokuqala.
   • Ukufunyanwa ngokukhawuleza: Iziphumo ziyafumaneka kwimizuzu engama-40.
   • Ukuhambelana okuqinileyo: Inokusetyenziswa ngeendlela ezahlukeneyoeqhelekileyoIinkqubo zePCR.

   -Uhlobo II luvuliweEudemon AIO800ILebhu yePCR ephathwayo

   

   • Isampulu Impendulo iphuma:Iskena ukulayisha ityhubhu yesampulu yoqobo kunye neekhatriji ezilungele ukusetyenziswa ukulungiselela ingxelo ezenzekelayo.
   • Ixesha lokuguqula ngokukhawuleza:Inika iziphumoinImizuzu engama-30, inceda izigqibo zeklinikhi ngexesha elifanelekileyo.
   • Uhlengahlengiso Oluguquguqukayo:4 iyakhutshwaiityhubhu zokusabelaukuxhobisa ukuzenzela ukudibanisa okubhetyebhetye kweemvavanyo ozidingayo.
   • Amanyathelo asibhozo okuthintela ukosuleleka:Umbhobho ojikelezayo, inkqubo yoxinzelelo olubi, ukuhluzwa kwe-HEPA, ukubulawa kweentsholongwane kwi-ultraviolet, ukuhlala wedwa ngokwasemzimbeni, ikhaka lokutshiza, itywina leoli yeparafini, ukukhuliswa okuvaliweyo.
   • Ulawulo lweReagent oluLula:Ama-reagents e-Lyophilized avumela ukugcinwa kwendawo kunye nokuhambat free ofulungiselelo lwekhonkco elibandayo.

   Njengoko theItekhnoloji iyaqhubeka nokuvela, kubalulekile kubasebenzi bezempilo ukuba bahlale bephambi kwegophe ngokuhlala behambisana nenkqubela phambili yamva nje yovavanyo lokuphefumla oluphindaphindiweyo.

   Hlala unolwazi-vumela iUxilongo oluchanekileyo lubumba ikamva elingcono.

   Qhagamshelanamarketing@mmtest.comukwandisa amandla akho okuxilongwa ukuqinisekisa iziphumo ezingcono zesigulana kunye nokhathalelo olusebenzayo ngakumbi.

   Isisombululo se-Syndromic Respiratory