Ukunganyangeki kweAntimicrobial (AMR) ibe sesinye sezona zoyikiso zempilo zoluntu kule nkulungwane, zibangela ngokuthe ngqo ngaphezulu kwe-1.27 yezigidi zokusweleka nyaka ngamnye kwaye kube negalelo kwizigidi ezi-5 zokubhubha ezongezelelweyo-le ngxaki yezempilo ingxamisekileyo ifuna ukuba sithathe amanyathelo akhawulezileyo.
Le Veki yeHlabathi yoKwazisa nge-AMR (ngoNovemba 18-24), iinkokeli zezempilo zehlabathi zimanyana kwikhwelo lazo:"Thatha ngoku: Khusela ubukho bethu, ukhusele ikamva lethu."Lo mxholo ugxininisa ukungxamiseka ekujonganeni ne-AMR, efuna iinzame ezilungelelanisiweyo kuwo wonke amacandelo empilo yabantu, impilo yezilwanyana kunye nokusingqongileyo.
Usongelo lwe-AMR ludlula imida yelizwe kunye nemimandla yezempilo. Ngokophononongo lwamva nje lweLancet, ngaphandle kokungenelela okusebenzayo ngokuchasene ne-AMR,Ukusweleka okongezelekayo kwihlabathi kunokufikelela kwizigidi ezingama-39 ngo-2050, ngelixa iindleko zonyaka zokunyanga usulelo olunganyangekiyo ngamachiza luqikelelwa ukuba lunyuke ukusuka kwi-R66 yeebhiliyoni zangoku ukuya kuthi ga ngoku.I-159 yeebhiliyoni zeedola.
Ingxaki ye-AMR: Inyani eMandundu emva kwamanani
Ukumelana ne-Antimicrobial (AMR) kwenzeka xa ii-microorganisms-ibhaktheriya, iintsholongwane, ii-parasites, kunye ne-fungi-zingasaphenduli kumayeza aqhelekileyo okulwa namagciwane. Le ngxaki yezempilo yehlabathi ifikelele kumlinganiselo owothusayo:
-Rhoqo ngemizuzu emi-5, umntu om-1 ubulawa sisifo esinganyangekiyo ngamayeza okubulala iintsholongwane
-Ngo2050, i-AMR inokunciphisa i-GDP yehlabathi nge-3.8%
-I-96% yamazwe(i-186 iyonke) ithathe inxaxheba kuphando lokulandela umkhondo lwe-AMR lwe-2024, ebonisa ukuqatshelwa ngokubanzi kwesi soyikiso.
-Kwiiyunithi zokhathalelo olunzulu kwezinye iindawo,ngaphezulu kwe-50% yeentsholongwane zebhaktiriyabonisa ukuxhathisa ubuncinane kwi-antibiotic enye
Ii-Antibiotics zisilela njani: IiMicroorganisms 'Defence Mechanisms
Ii-antibiotics zisebenza ngokujolisa kwiinkqubo ezibalulekileyo zebhaktiriya:
-Udibaniso lweWall yeeseli: Iipenicillin ziphazamisa iindonga zeeseli zebhaktiriya, zibangela ukugqabhuka kwebhaktiriya nokufa
-Ukuveliswa kweeProtheyiniI-Tetracyclines kunye ne-macrolides zithintela i-ribosomes yebhaktiriya, zimisa ukuhlanganiswa kweeprotheyini
-DNA/RNA Replication: I-Fluoroquinolones inqanda i-enzymes efunekayo kwi-bacterial DNA replication
-IMfezeko yeMembrane yeSeli: Iipolymyxins zonakalisa iiseli ze-bacterial membranes, ezikhokelela ekufeni kweeseli
-Iindlela zeMetabolic: IiSulfonamides zivimba iinkqubo ezibalulekileyo zebhaktiriya njengefolic acid synthesis
Nangona kunjalo, ngokukhethwa kwendalo kunye nokuguqulwa kofuzo, iibhaktheriya ziphuhlisa iindlela ezininzi zokuchasa i-antibiotics, kubandakanywa nokuvelisa i-enzymes engasebenzi, ukuguqula iithagethi zamachiza, ukunciphisa ukuqokelelwa kweziyobisi, kunye nokwenza i-biofilms.
I-Carbapenemase: "Isixhobo esiPhezulu" kwiNgxaki ye-AMR
Phakathi kweendlela ezahlukeneyo zokumelana, ukuveliswa kwei-carbapenemasiphathelene ngakumbi. Ezi enzymes i-hydrolyze i-carbapenem antibiotics-ngokuqhelekileyo ithathwa njengeziyobisi "zomgca wokugqibela". I-Carbapenemases isebenza njengebhaktiriya "izixhobo eziphezulu," ukuphula i-antibiotics ngaphambi kokuba ingene kwiiseli zebhaktheriya. Iintsholongwane ezithwala ezi enzymes-ezifana neKlebsiella inyumoniyakwayeAcinetobacter baumannii—iyakwazi ukuphila kwaye iphindaphindeke naxa idibene neyona ntsholongwane inamandla.
Okothusayo ngakumbi kukuba, iijini ezifaka i-carbapenemases zibekwe kwizinto eziphathwayo zemfuzo ezinokudluliselwa phakathi kweentlobo ezahlukeneyo zebhaktiriya,ukukhawulezisa ukusasazeka kwehlabathi kwebhaktiriya enganyangekiyo ngamachiza.
Uxilongos: Umgca wokuQala woKhuselo kuLawulo lwe-AMR
Uxilongo oluchanekileyo, olukhawulezayo lubalulekile ekulweni ne-AMR. Ukuchongwa kwangethuba kweebhaktheriya ezixhathisayo kunoku:
-Khokela unyango oluchanekileyo, ukuphepha ukusetyenziswa kwe-antibiotic engasebenziyo
-Sebenzisa amanyathelo okulawula usulelo ukuthintela usulelo lwebhaktheriya exhathisayo
-Beka iliso kwiindlela zokuxhathisa ukwazisa izigqibo zempilo yoluntu
Izisombululo zethu: Izixhobo ezitsha zokuLwa kwe-AMR echanekileyo
Ukujongana nomngeni okhulayo we-AMR, i-Macro kunye ne-Micro-Test iye yavelisa iikiti ezintathu zokufumanisa i-carbapenemase ezihlangabezana neemfuno ezahlukeneyo zekliniki, ukunceda ababoneleli bezempilo ngokukhawuleza nangokuchanekileyo ukuchonga iibhaktheriya ezixhathisayo ukuze kuqinisekiswe ukungenelela kwangethuba kunye nokuphucula iziphumo zesigulane.
1. IKit yokuFumana iCarbapenemase (iGolide yeColloidal)
Isebenzisa itekhnoloji yegolide ye-colloidal ukufunyanwa ngokukhawuleza, okuthembekileyo kwe-carbapenemase. Ifanelekile kwizibhedlele, iikliniki, kunye nokusetyenziswa kwekhaya, ukwenza lula inkqubo yokuxilongwa ngokuchaneka okuphezulu.
Izinto eziluncedo ezingundoqo:
-UFundo oluBanzi: Ngaxeshanye ichonga iindlela ezintlanu zokuxhathisa—NDM, KPC, OXA-48, IMP, kunye neVIM
-Iziphumo eziKhawulezayo: Ibonelela ngeziphumo ngaphakathiImizuzu eli-15, ngokukhawuleza kakhulu kuneendlela zemveli (iintsuku ezi-1-2)
-Easy Operation: Akukho zixhobo ezintsonkothileyo okanye uqeqesho olukhethekileyo olufunekayo, olufanelekileyo kwiisetingi ezahlukeneyo
-Ukuchaneka okuphezulu: I-95% yobuntununtunu obungenazo iimpawu zobuxoki ezivela kwiibhaktheriya eziqhelekileyo ezifana neKlebsiella pneumoniae okanye iPseudomonas aeruginosa
2. I-Carbapenem Resistance Gene Detection Kit (Fluorescence PCR)
Yenzelwe uhlalutyo olunzulu lwemfuza yokumelana ne-carbapenem. Ilungele ukucupha olubanzi kwiilebhu zeklinikhi, ukubonelela ngokuchongwa ngokuchanekileyo kweendlela ezininzi zokumelana ne-carbapenem.
Izinto eziluncedo ezingundoqo:
-Isampulu eguquguqukayo: Ubhaqo ngqo ukusukaamakholoni acocekileyo, isikhohlela, okanye i-rectal swabs-akukho nkcubekoefunekayo
-UkuNcitshiswa kweendleko: Ifumanisa iijene ezithandathu zokumelana (NDM, KPC, OXA-48, OXA-23) IMP, kunye ne-VIM kuvavanyo olulodwa, ukuphelisa uvavanyo olungafunekiyo
-Uvakalelo oluPhezulu kunye nokuNgcaciswa: Umda wokufumanisa uphantsi njenge-1000 CFU / mL, akukho-cross-reactivity kunye nezinye izakhi zokumelana ezifana ne-CTX, i-mecA, i-SME, i-SHV, kunye ne-TEM
-Ukuhambelana okubanzi: IyahambelanaIsampulu-kwiMpenduloI-AIO 800 i-POCT yeemolekyuli ezizenzekelayo ngokupheleleyo kunye nezixhobo zePCR eziqhelekileyo
3. I-Klebsiella pneumoniae, i-Acinetobacter baumannii, i-Pseudomonas aeruginosa kunye ne-Resistance Genes Multiplex Detection Kit (i-Fluorescence PCR)
Le khithi idibanisa ukuchongwa kwebhaktheriya kunye neendlela zokuxhathisa ezinxulumene nenkqubo enye elungelelanisiweyo yokuxilongwa ngokufanelekileyo.
Izinto eziluncedo ezingundoqo:
-UFundo oluBanzi: Ichonga ngaxeshanyeiintsholongwane ezintathu eziphambili zebhaktiriya-I-Klebsiella pneumoniae, i-Acinetobacter baumannii, kunye ne-Pseudomonas aeruginosa-kwaye ifumanisa iigenes ezine ezibalulekileyo ze-carbapenemase (KPC, NDM, OXA48, kunye ne-IMP) kuvavanyo olunye.
-Uvakalelo oluPhezulu: Iyakwazi ukufumanisa i-DNA yebhaktiriya kwiindawo eziphantsi njenge-1000 CFU / mL
-Ixhasa iSigqibo soNyango: Iququzelela ukhetho lonyango olusebenzayo lwe-antimicrobial ngokuchongwa kwangoko kweentlobo ezixhathisayo
-Ukuhambelana okubanzi: IyahambelanaIsampulu-kwiMpenduloI-AIO 800 i-POCT yeemolekyuli ezizenzekelayo ngokupheleleyo kunye nezixhobo zePCR eziqhelekileyo
Ezi zixhobo zokufumanisa zibonelela ngabaqeqeshi bezempilo ngezixhobo zokujongana ne-AMR kumanqanaba ahlukeneyo-ukusuka kuvavanyo olukhawulezayo lokujonga uhlalutyo olucacileyo lwemfuza-ukuqinisekisa ukungenelela ngexesha kunye nokunciphisa ukusasazeka kweebhaktheriya ezichasayo.
Ukulwa ne-AMR kunye ne-Precision Diagnostics
Kwi-Macro & Micro-Test, sibonelela ngeekiti zokuxilonga ezixhobisa ababoneleli bezempilo ngokukhawuleza, ukuqonda okuthembekileyo, okwenza uhlengahlengiso lonyango olungexesha kunye nolawulo olusebenzayo losulelo.
Njengoko kugxininiswe kwiVeki yokuQatshelwa kwe-AMR yeHlabathi, ukhetho lwethu namhlanje luya kugqiba amandla ethu okukhusela izizukulwana zangoku kunye nezizayo kwisoyikiso sokuchasana ne-antimicrobial.
Joyina umlo wokuchasana ne-antimicrobial-bonke ubomi obusindisiweyo bubalulekile.
For more information, please contact: marketing@mmtest.com
Ixesha lokuposa: Nov-19-2025