Yintoni i-HPV?
I-Human Papillomavirus (HPV) yenye yezona zifo zixhaphakileyo zesondo (ii-STI) kwihlabathi liphela. Liqela leentsholongwane ezingaphezulu kwama-200 ezinxulumene nazo, kwaye malunga nama-40 azo anokosulela indawo yesini, umlomo, okanye umqala. Ezinye iintlobo ze-HPV azinabungozi, ngelixa ezinye zinokubangela iingxaki zempilo ezinzulu, kubandakanya umhlaza wesibeleko kunye neentsholongwane zesini.
Ixhaphake kangakanani i-HPV?
I-HPV ixhaphake kakhulu. Kuqikelelwa ukuba malungaAma-80% abafazi kunye nama-90% amadodabaza kosulelwa yi-HPV ngaxa lithile ebomini babo. Uninzi lwezifo ziyaphela zodwa, kodwa ezinye iintlobo ezinobungozi obukhulu zinokuhlala zikhokelele kumhlaza ukuba azibonwanga.
Ngubani osengozini?
Ngenxa yokuba i-HPV ixhaphake kakhulu kangangokuba uninzi lwabantu ababelana ngesondo basengozini (kwaye ngaxa lithile baya kuba nayo) intsholongwane ye-HPV.
Izinto ezinxulumene neumngcipheko ophezulu wosulelo lwe-HPVziquka:
l Ukwabelana ngesondo okokuqala usemncinci (ngaphambi kokuba uneminyaka eli-18);
Ukuba namaqabane amaninzi esondo;
Ukuba neqabane elinye lesondo elinamaqabane amaninzi esondo okanye elinosulelo lwe-HPV;
Ukuba namasosha omzimba abuthathaka, njengabantu abaphila ne-HIV;
Kutheni Kubalulekile Ukuchonga I-Genotyping
Ayizizo zonke izifo ze-HPV ezifanayo. Iintlobo ze-HPV zahlulwe zibe ngamaqela amathathu:
1.Umngcipheko ophezulu (HR-HPV) – Inxulunyaniswa nomhlaza ofana nomhlaza womlomo wesibeleko, umhlathi womqolo, kunye nomhlaza wamazinyo.
2.Prmhlawumbi ezinobungozi obuphezulu (pHR-HPV)– Isenokuba negalelo elithile kwi-oncogenic.
3.Umngcipheko ophantsi (LR-HPV)– Ngokwesiqhelo kubangela iimeko ezingengozini ezifana neentsumpa zesini.
Ukwazi uhlobo oluthile lwe-HPVKubalulekile ukumisela inqanaba lomngcipheko kunye nokugqiba ulawulo olufanelekileyo okanye icebo lonyango. Iintlobo ezinobungozi obukhulu zifuna ukubekwa esweni ngokusondeleyo, ngelixa iintlobo ezinobungozi obuphantsi zihlala zifuna nje ukukhululeka kwiimpawu.
Ukwazisa uvavanyo olupheleleyo lwe-HPV 28 Genotypes
Isisombululo sokuchwetheza se-HPV 28 seMacro kunye neMicro-Testluvavanyo olusemgangathweni ophezulu, oluvunyiweyo yi-CE oluzisaukuchaneka, isantya, kunye nokufikelelekauvavanyo lwe-HPV.
Oko Kukwenzayo:
1.Ifumanisa ii-genotypes ezingama-28 ze-HPVkuvavanyo olunye—oluquka iintlobo ezili-14 ze-HR-HPV kunye neentlobo ezili-14 ze-LR-HPV, kuquka neentlobo ezibaluleke kakhulu ngokwezonyango:
6, 11, 16, 18, 26, 31, 33, 35, 39, 40, 42, 43, 44, 45, 51, 52, 53, 54, 56, 58, 59, 61, 66, 68, 73, 81, 82, 83
2.Igubungela zombini iintlobo ezibangela umhlaza womlomo wesibeleko kunye nezo zibangela iintsumpa zesini, okuvumela uvavanyo olupheleleyo lomngcipheko.
Kutheni Kwahlukile:
1.Uvakalelo oluphezulu:Ifumanisa i-DNA yentsholongwane kwiIikopi ezingama-300/mL, okuvumela ukuba kubonwe usulelo olukwinqanaba lokuqala okanye olunomthwalo omncinci.
2. Utshintsho olukhawulezileyo:Iziphumo ze-PCR zilungile kungekudalaIiyure eziyi-1.5, okuvumela ukuba kwenziwe izigqibo zonyango ngokukhawuleza.
3. Ulawulo lwangaphakathi oluBini:Ithintela iziphumo ezingezizo ezilungileyo kwaye iphucula ukuthembeka kweziphumo.
4. Isampuli eguquguqukayo:Inkxasoiiswabhu zomlomo wesibelekokwayeukwenza iisampulu ngokwakho ngokusekelwe kumchamo, ukwandisa ukulula nokufikeleleka.
5. Iinketho ezininzi zokukhupha:Iyahambelana neesekelwe kwiintsimbi zemagnethi, ikholamu yokujikelezaokanyei-lysis ethe ngqoimizekelo yokusebenza yokulungiselela isampuli.
6. Iifomathi ezimbini ezikhoyo:Khethaulwelookanyei-lyophilizediinguqulelo—iinkxaso zefomu ezi-lyophilizedindawo yokugcina nokuthumela ubushushu begumbi, ilungele useto olukude okanye olunezixhobo ezimbalwa.
7.Ukuhambelana kwe-Broad PCR:Idibana kakuhle neenkqubo ezininzi ze-PCR kwihlabathi liphela.
Okungaphezulu Kokuchongwa Nje—Yinzuzo Yezonyango
Ukubhala ngokuchanekileyo i-HPV kubalulekileukuthintela, ukufunyanwa kwangethuba, kunye nolawulo lweklinikhiyomhlaza womlomo wesibeleko neminye i-HPV. Olu vavanyo alupheleli nje ekufumaneni i-HPV—lumalunga nokunika izigulane kunye noogqirha ulwazi oluchanekileyo abaludingayo ukuze benze ngokuzithemba nangokukhawuleza.
Nokuba ungumntuugqirha, ailebhu yokuxilonga, okanyeumsasazi, iI-HPV 28UkuthayiphaUvavanyoibonelelayanamhlanje, epheleleyo, kwaye ifikeleleka lulaisisombululo seengxaki zempilo zanamhlanje.
Nika amandla iinkqubo zakho zokuhlola nokuthintelange-Macro & Micro-Test's HPV 28 Typing Solution—kuba ukuchaneka kunye nokungenelela kwangoko kubalulekile.
Qhagamshelana nathi namhlanjeukuze ufunde ngakumbi ngamathuba obudlelwane, ukuphunyezwa kweklinikhi, okanye iinkcukacha zemveliso.
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Ixesha lokuthumela: Okthobha-22-2025