Uphononongo olubalulekileyo lwakutshanje olupapashwe kwiI-Lancetityhile inyani ephazamisayo:Abantu ababhubhileyo abazizigidi ezili-1.27 ngo-2019zazibangelwa ngokuthe ngqoukuxhathisa iintsholongwane (AMR). Oyikisa nangakumbi,Ama-73% aba bantu bafayo abangelwa ziintsholongwane ezintandathu kuphela.:

1.I-Escherichia coli

2.I-Staphylococcus aureus

3.I-Klebsiella pneumoniae

4.I-Streptococcus pneumoniae

5.I-Acinetobacter baumannii

6.I-Pseudomonas aeruginosa

Phakathi kwabo,I-Klebsiella pneumoniae (KPN), I-Acinetobacter baumannii (Aba)kunyeI-Pseudomonas aeruginosa (PA)zibonakala njengezinegalelo elikhulu kwizifo ezifunyanwa esibhedlele kunye nokunganyangeki kwamayeza amaninzi. Ezi zifo ziya zixhathisa ngakumbiii-carbapenems—umgca wethu wokugqibela wokuzikhusela—obeka umngcipheko omkhulu kwimpilo yehlabathi.

Ukuqonda i-KPN, i-Aba, kunye ne-PA

-I-Klebsiella pneumoniae (KPN)

I-KPN yintsholongwane eqhelekileyo enobungozi kwaye yeyona nto iphambili ebangelaisibhedlele esifunyenweyousuleloXa amandla okuzikhusela komzimba ebuthathaka, anokungena ngendlela yokuphefumla, nto leyo ebangela i-pneumonia, usulelo lwegazi, kunye ne-sepsis. Okuxhalabisayo ngakumbi kukubauhlobo lwe-hvKp ST23 olunamandla kakhulu, edla ngokuthwala ii-carbapenem zejini ezifana neI-KPC, i-NDM, i-OXA-48, kunye ne-IMP, okwenza unyango lube nzima kakhulu.

-I-Acinetobacter baumannii (Aba)

I-Aba yintsholongwane ekwaziyo ukumelana nezifo esibhedlele, ekwaziyo ukuhlala phezu komhlaba ixesha elide. Yimbangela enkulu yale ntsholongwane.i-pneumonia enxulumene nomoya wokungenisa umoya (VAP)kunye nosulelo olunxulumene ne-ICU. Amandla ayo angaqhelekanga okufumana iijini zokuxhathisa ayenze yaba yenye yezona ziyingozi kakhuluiintsholongwane ezinganyangekiyo ngamayeza amaninzi (MDR), kunye nokumelana ne-carbapenem okungaphezulu50% kwezinye iindawo.

-I-Pseudomonas aeruginosa (PA)

I-PA yintsholongwane engavundiyo i-Gram-negative ebangelaizifo ezisezantsi zendlela yokuphefumla, ingakumbi kwizigulane ezibuthathaka kumasosha omzimba. Ukuziqhelanisa kwayo, izinga lokuguquka ngokukhawuleza, kunyeubuchule bokwenza i-biofilmkwenza kube nzima ukuphelisa izifo.Carbapenem-resistant PA (CRPA)isengumngeni wezonyango oqhubekayo kwihlabathi liphela.

Indlela Ezi Ntsholongwane Ezisasazeka Ngayo

Iintsholongwane ze-MDR zisasazeka kakhulu nge:

-Iindawo ezingqongileyo zesibhedlele:izixhobo, imiphezulu, kunye nezandla zabasebenzi bezempilo ezingcolisiweyo

-Unxibelelwano ngqo:izigulane ezineentsholongwane okanye abathwali abangenazo iimpawu

-Amathontsi okuphefumla:ngakumbi kwiintlobo ezinxulumene ne-pneumonia

-Iinkqubo zokungenelela:ii-ventilators, ii-catheters, kunye nezixhobo zotyando

Imingeni kuNyango

-Ukumelana neCarbapenem

IiCarbapenems zithathwa njengezinto ezisetyenziswa kakhuluamayeza okubulala iintsholongwane okugqibelaUkuvela kweebhaktheriya ezivelisa i-carbapenemase kuye kwanciphisa kakhulu ukusebenza kwazo.

-Iindlela Ezincinci Zonyango

-IiPolymyxins (umz., i-colistin): ziyasebenza kodwa zinobuthi kakhulu

-Tigecycline: iimpawu ezilinganiselweyo

-Iiarhente ezintsha (cefiderokol, sulbactam-durlobactam): ziyathembisa kodwa azifumaneki lula

Ukuthintela kunye nokuchongwa kwangoko ngoku kubaluleke kakhulu kunangaphambili.

Imfuneko Yokuchongwa Okukhawulezileyo Nokuchanekileyo

Ezi ntsholongwane zibangela inxalenye enkulu yokufa okunxulumene ne-AMR kwihlabathi liphela, nto leyo ebonisa imfuneko engxamisekileyo yokubaukuxilongwa okukhawulezayo nokuthembekileyoukukhokela unyango olufanelekileyo.

Ukufunyaniswa Kwangethuba Kusindisa Ubomi

Ukujongana nale mfuno ingxamisekileyo yeklinikhi,Ikhithi yokuFumana i-Macro kunye ne-Micro-Test's KPN, Aba, PA kunye ne-Drug Resistance Genes Multiplexinika isisombululo esinamandla.

Isisombululo esitsha,Ikhithi yokuFumanisa i-Multiplex yeMacro kunye neMicro-Test, ivumela ukuchongwa ngaxeshanye kweI-KPN, i-Aba, i-PA, kunye ne-key carbapenemase genes-I-KPC, I-NDM, I-OXA-48kunyeI-IMP.

Iingenelo eziphambili:

• Ukufunyanwa ngokuthe ngqo kwiisampuli zesikhohlela, ukuphelisa iinkqubo zokulima ezinde.
• Ukucaciswa okuphezulu kunye novakalelo(LoD: 1000 CFU/mL) ukuze ufumane iziphumo ezichanekileyo.
• Ixesha lokuphendula ngokukhawuleza—liphumela kwi-35 kuphela-50imizuzu.
• Iyahambelana neenkqubo zePCR eziphambili, ukuqinisekisa ukufikeleleka ngokubanzi.

Isibhengezo Sokwenza: Ukuqinisa Ukulwa Nee-Superbugs

PhambiliIkhithi yokuFumanisa iMultiplexsnguUvavanyo lweMacro kunye nolweMicro Ibonelela ngenzuzo ebalulekileyo ekuchongeni iintsholongwane ezinganyangekiyo ngokukhawuleza nangokuchanekileyo, ivumela ukujongwa kwangaphambili, ukuxilongwa ngokukhawuleza, kunye namaqhinga okunyanga ajoliswe kuwo, nto leyo ekugqibeleni iphucula iziphumo zesigulana kwaye ilawule ukusasazeka kokunganyangeki kwee-antibiotic.

Joyina idabi lokulwa nokuxhathisa iintsholongwane—xhobisa ilabhoratri yakho ngesixhobo sokuxilonga esisemgangathweni ophezulu.

Contact if interested: marketing@mmtest.com