I-Candida Albicans Nucleic Acid
Igama lemveliso
Ikhithi yokuFumana i-HWTS-FG005-Nucleic Acid esekwe kwi-Enzymatic Probe Isothermal Amplification (EPIA) yeCandida Albicans
Isatifikethi
CE
I-Epidemiology
Uhlobo lweCandida lolona hlobo lwezityalo luqhelekileyo lwefungus emzimbeni womntu, olufumaneka kakhulu kwindlela yokuphefumla, kwindlela yokugaya ukutya, kwindlela yokuzala kunye nezinye izitho ezinxibelelana nehlabathi langaphandle. Alunazo izifo ngokubanzi kwaye luvela kwiibhaktheriya ezibangela izifo ezixhomekeke kwiimeko ezithile. Ngenxa yokusetyenziswa okukhulu kwee-immunosuppressive agents, uphuhliso lwe-tumor radiotherapy, i-chemotherapy, unyango oluhlaselayo, kunye nokufakelwa kwamalungu omzimba, kunye nokusetyenziswa ngokubanzi kwenani elikhulu lee-antibiotics ze-broad-spectrum, iintyatyambo eziqhelekileyo azilingani, nto leyo ekhokelela kwiintsholongwane zeCandida kwindlela yokuzala kunye nendlela yokuphefumla.
Usulelo lweCandida kwindlela yokuzala lunokubangela ukuba abafazi bahlupheke yi-candidiasis kunye ne-vaginitis, kwaye lubangele ukuba amadoda ahlupheke yi-candidiasis, i-acroposthitis kunye ne-prostatitis, ezichaphazela kakhulu ubomi nomsebenzi wezigulana. Izinga lokuxhaphaka kwe-candidiasis kwindlela yokuzala liyanda minyaka le. Phakathi kwazo, usulelo lwe-candidiasis kwindlela yokuzala yabasetyhini lumalunga ne-36%, kwaye amadoda amalunga ne-9%, kwaye usulelo lweCandida albicans (CA) zezona ziphambili, zimalunga ne-80%.
Usulelo lwefungus oluqhelekileyo kwiCandida albicans luyimbangela ebalulekileyo yokufa ngenxa yosulelo lwe-nosocomial. Phakathi kwezigulana ezibalulekileyo kwi-ICU, usulelo lweCandida albicans lubalelwa malunga nama-40%. Phakathi kwazo zonke izifo zefungus zesisu, usulelo lwefungus lwemiphunga lolona luninzi kwaye luyanda minyaka le. Ukuxilongwa kwangoko kunye nokuchongwa kosulelo lwefungus yemiphunga kubaluleke kakhulu kwezonyango.
Iingxelo zeklinikhi zangoku ze-genotypes ze-Candida albicans ziquka uhlobo A, uhlobo B, kunye nohlobo C, kwaye ezi genotypes zintathu zingaphezulu kwe-90%. Ukuxilongwa ngokuchanekileyo kosulelo lwe-Candida albicans kunokubonelela ngobungqina bokuxilongwa kunye nonyango lwe-candidal vulvitis kunye ne-vaginitis, i-candidal balanitis yamadoda, i-acroposthitis kunye ne-prostatitis, kunye nosulelo lwe-Candida albicans kwindlela yokuphefumla.
Itshaneli
| I-FAM | I-asidi ye-nucleic ye-CA |
| I-ROX | Ulawulo lwangaphakathi |
Iiparameters zobugcisa
| Indawo yokugcina izinto | Ulwelo: ≤-18℃ Ebumnyameni; I-Lyophilized: ≤30℃ Ebumnyameni |
| Beka ubomi kwishelufa | Ulwelo: Iinyanga ezili-9; I-Lyophilized: Iinyanga ezili-12 |
| Uhlobo lweSibonelelo | I-Sputum, i-Sputum, i-Sputum, kunye ne-Sputum |
| Tt | ≤28 |
| CV | ≤10.0% |
| I-LoD | Iikopi ezi-5/µL, iibhaktheriya ezili-102/mL |
| Ukuchaneka | Akukho kudibana kwe-reactivity nezinye iintsholongwane ze-genitourinary tract infections, ezifana ne-Candida tropicalis, i-Candida glabrata, i-Trichomonas vaginalis, i-Chlamydia trachomatis, i-Ureaplasma urealyticum, i-Neisseria gonorrhoeae, i-Group B streptococcus, i-Herpes simplex virus type 2, njl.njl.; akukho kudibana kwe-reactivity phakathi kwale kit kunye nezinye iintsholongwane ze-respiral infections, ezifana ne-Adenovirus, i-Mycobacterium tuberculosis, i-Klebsiella pneumoniae, i-Maasles, i-Candida tropicalis, i-Candida glabrata kunye neesampuli ze-sputum eziqhelekileyo zomntu, njl.njl. |
| Izixhobo Ezisebenzayo | Inkqubo yokuFumanisa i-Easy Amp Real-time Fluorescence Isothermal (HWTS1600) Iinkqubo ze-PCR ze-Applied Biosystems 7500 Real-Time Iinkqubo ze-PCR eziSebenzisiweyo ze-7500 ezikhawulezayo zeXesha langempela Iinkqubo ze-PCR zeQuantStudio®5 zeXesha langempela Iinkqubo ze-PCR ze-SLAN-96P zeXesha langempela Inkqubo ye-PCR yeLightCycler®480 yeXesha langempela Inkqubo yokuHlola i-PCR yeLineGene 9600 Plus ngexesha langempela I-MA-6000 Real-Time Quantitative Thermal Cycler Inkqubo ye-PCR ye-BioRad CFX96 yeXesha langempela Inkqubo ye-PCR ye-BioRad CFX Opus 96 yeXesha langempela |
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