Carbapenemase

Inkcazelo emfutshane:

Le kit isetyenziselwa ukufumanisa umgangatho we-NDM, i-KPC, i-OXA-48, i-IMP kunye ne-VIM carbapenemases eveliswe kwiisampuli zebhaktheriya ezifunyenwe emva kwenkcubeko kwi-vitro.

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Igama lemveliso

I-HWTS-OT085E/F/G/H -I-Carbapenemase ye-Detection Kit (i-Colloidal Gold)

I-Epidemiology

I-Carbapenem antibiotics zi-atypical β-lactam antibiotics kunye ne-antibacterial spectrum ebanzi kunye nomsebenzi onamandla we-antibacterial.^[1]. Ngenxa yokuzinza kwayo kwi-β-lactamase kunye netyhefu ephantsi, iye yaba yenye yezona ziyobisi zibalulekileyo kunyango losulelo olubi lwebhaktiriya. I-Carbapenems izinzile kakhulu kwi-plasmid-mediated extended-spectrum β-lactamases (ESBLs), i-chromosomes kunye ne-plasmid-mediated cephalosporinases (i-AmpC enzymes)^[2].

Iiparamitha zobuGcisa

Ummandla ekujoliswe kuwo	NDM, KPC, OXA-48, IMP kunye ne-VIM carbapenemases
Ubushushu bokugcina	4℃-30℃
Uhlobo lwesampuli	Iisampuli zebhaktheriya ezifunyenwe emva kwenkcubeko
Beka ubomi kwishelufa	Iinyanga ezingama-24
Izixhobo ezincedisayo	Ayifuneki
Izinto ezisetyenziswayo ezongezelelweyo	Ayifuneki
Ixesha lokubona	Iisampuli zebhaktheriya ezifunyenwe emva kwenkcubeko
LoD	NDM uhlobo:0.15ng/mL Uhlobo lwe KPC: 0.4ng/mL OXA-48 uhlobo:0.1ng/mL Uhlobo lwe-IMP:0.2ng/mL Uhlobo lweVIM:0.3ng/mL.
isiphumo hook	Kwi-NDM, i-KPC, i-OXA-48 yohlobo lwe-carbapenemase, akukho siphumo se-hook sifumaneka kuluhlu lwe-100ng / mL; kwi-IMP, i-VIM yohlobo lwe-carbapenemase, akukho siphumo se-hook sifumaneka kuluhlu lwe-1μg / mL.