I-Dengue Virus IgM/IgG Antibody

Le mveliso ifanelekile ukufunyaniswa okusemgangathweni kwe-antibodies ye-dengue virus, kuquka i-IgM kunye ne-IgG, kwi-serum yabantu, i-plasma kunye neesampuli zegazi elipheleleyo.

I-Dengue fever sisifo esosulelayo esibangelwa yintsholongwane yedengue, kwaye sesinye sezifo ezosulelayo ezisasazwa kakhulu ziingcongconi ehlabathini. Ngokwe-serological, yohlulwe kwii-serotypes ezine, i-DENV-1, i-DENV-2, i-DENV-3, kunye ne-DENV-4^[1]. Intsholongwane yeDengue inokubangela uluhlu lweempawu zeklinikhi. Ngokwezonyango, ezona mpawu ziphambili yifiva ephezulu ngesiquphe, ukopha okukhulu, iintlungu eziqatha kwizihlunu kunye neentlungu zamalungu, ukudinwa okugqithisileyo, njl. njl., kwaye zihlala zihamba nerhashalala, i-lymphadenopathy kunye ne-leukopenia.^[2]. Ngokunyuka kobushushu behlabathi, ukusasazwa ngokwejografi komkhuhlane wedengue kuthanda ukunwenwa, kwaye izehlo kunye nobuzaza bobhubhane nabo bayanda. I-Dengue fever ibe yingxaki enkulu yempilo yoluntu jikelele.

Le mveliso ikhawuleza, ikwisiza kunye nekhithi echanekileyo yokufumanisa i-antibody ye-dengue virus (IgM/IgG). Ukuba kukho i-antibody ye-IgM, ibonisa usulelo lwakutsha nje. Ukuba kukho i-antibody ye-IgG, ibonisa ixesha elide losulelo okanye usulelo oludlulileyo. Kwizigulane ezinosulelo oluphambili, ii-antibodies ze-IgM zingabonwa iintsuku ezi-3-5 emva kokuqala, kunye nencopho emva kweeveki ezi-2, kwaye zingagcinwa kwiinyanga ezi-2-3; Izilwa-buhlungu ze-IgG zinokufunyaniswa kwiveki enye emva kokuqala, kwaye izilwa-buhlungu ze-IgG zinokugcinwa iminyaka emininzi okanye ubomi bonke. Kwiveki ye-1, Ukuba ukufunyanwa kwenqanaba eliphezulu le-antibody ye-IgG ethile kwi-serum yesigulana kwiveki enye yokuqala, kubonisa ukusuleleka kwesibini, kwaye isigwebo esibanzi sinokwenziwa ngokubambisana nomlinganiselo we-antibody ye-IgM / IgG efunyenwe yindlela yokubamba. Le ndlela ingasetyenziswa njengesongezelelo kwiindlela zokubona i-viral nucleic acid.