I-Mycobacterium Tuberculosis Rifampicin Resistance
Igama lemveliso
HWTS-RT074A-Mycobacterium Tuberculosis Rifampicin Resistance Detection Kit (Fluorescence PCR)
I-Epidemiology
I-Rifampicin isetyenziswe ngokubanzi kunyango lwezigulane ze-pulmonary tuberculosis ukususela ekupheleni kwe-1970s, kwaye inesiphumo esibalulekileyo.Kuye kwaba yinto yokuqala yokukhetha ukunciphisa i-chemotherapy yezigulane ze-pulmonary tuberculosis.Ukumelana ne-Rifampicin kubangwa ikakhulu kukuguqulwa kwejini ye-rpoB.Nangona amachiza amatsha okulwa nesifo sephepha ehlala ephuma, kunye nokusebenza kwezonyango kwizigulana zesifo sephepha semiphunga nako kuqhubekile ukuphucuka, kusekho ukunqongophala kweziyobisi ezichasene nesifo sephepha, kwaye isenzeko sokusetyenziswa kweziyobisi ngokungekho ngqiqweni ekliniki siphezulu.Ngokucacileyo, isifo sephepha seMycobacterium kwizigulane ezine-pulmonary tuberculosis ayikwazi ukubulawa ngokupheleleyo ngexesha elifanelekileyo, ekugqibeleni likhokelela kwiinqanaba ezahlukeneyo zokunganyangeki kweziyobisi emzimbeni wesigulane, kwandisa ixesha lesi sifo, kwaye kwandisa umngcipheko wokufa kwesigulane.Le khithi ilungele uxilongo oluncedisayo losulelo lwesifo sephepha seMycobacterium kunye nokufunyanwa kwejini yokuxhathisa i-rifampicin, eluncedo ukuqonda ukuxhathisa kumachiza esifo sephepha se-mycobacterium esosulelwe zizigulane, kunye nokubonelela ngeendlela ezincedisayo kwisikhokelo samayeza ezonyango.
I-Epidemiology
| Igama ekujoliswe kulo | Intatheli | Ukucima | ||
| Isithinteli sokuphendulaA | Isithinteli sokuphendulaB | Isithinteli sokuphendulaC | ||
| rpoB 507-514 | rpoB 513-520 | IS6110 | FAM | Akukho nanye |
| rpoB 520-527 | rpoB 527-533 | / | CY5 | Akukho nanye |
| / | / | Ulawulo lwangaphakathi | I-HEX(VIC) | Akukho nanye |
IiParameters zobuGcisa
| Ugcino | ≤-18℃ ebumnyameni |
| Beka ubomi kwishelufa | Iinyanga ezili-9 |
| Uhlobo loMfanekiso | Isikhohlela |
| CV | ＜5％ |
| LoD | uhlobo lwasendle oluxhathisa i-rifampicin: 2x103ibhaktheriya/mL i-homozygous mutant: 2x103ibhaktheriya/mL |
| Ukuchaza ngokuthe ngqo | Ibhaqa i-mycobacterium tuberculosis yohlobo lwasendle kunye neziza zotshintsho zezinye iindlela zokumelana neyeza ezifana ne-katG 315G>C\A, InhA-15C>T, iziphumo zovavanyo zibonisa ukunganyangeki kwi-rifampicin, into ethetha ukuba akukho kuphinda-phinda kusebenze. |
| Izixhobo Ezisebenzayo: | SLAN-96P Iinkqubo zePCR zeXesha lokwenyani(Hongshi Medical Technology Co., Ltd.) |
Ukuhamba komsebenzi
