Ukususela ngoMeyi 2022, amatyala e-MPOX axelwe kumazwe amaninzi angesosiphelo emhlabeni nothuthuzelo loluntu.
Nge-26 ka-Agasti, uMbutho wezeMpilo weHlabathi (i-WHO) esungule ihlabathi liphelaUkulungiswa kweqhinga kunye nesicwangciso sokuphendulaUkuyeka ukuqhuma kosulelo lwabantu ukuya kwi-MPOX nge-MPOX ngemizamo yehlabathi, yengingqi, kunye neyesizwe. Oku kulandela oku kubhengezwa kwengxamiseko yezempilo yoluntu yenkxalabo yeHlabathi yeHlabathi nguLowo uMlawuli-Jikelele nge-14 ka-Agasti.
Kufuneka iqatshelwe ukuba uqhambuka i-MPOX ngeli xesha yahlukile ku-2022, eyayisasazeka kakhulu phakathi kwamadoda anesondo nabantu abosulelekileyo babengaphantsi kwe-1%.
I-Surin yakutshanje ye-Speed "ye-Ib", eyahluka kwe-CODE i, inezinga eliphezulu lokufa. Oku kwahluka okutsha kwaqala ukusasazeka kwi-DRC yokugqibela, ekuqaleni kwabantu abathengisa ngesondo, kwaye ngoku basasazeke kwamanye amaqela, nabantwana bebechaphazeleka ikakhulu.
I-Afrika ye-Afrika yatsho ingxelo kwingxelo ephelileyo yokuba ukuqhuma kwee-MPOX kufumaneka kumazwe ali-10 ase-Afrika kulo nyaka, kubandakanya i-DRC, enike ingxelo ye-DRC, enike ingxelo ye-DRC, enike ingxelo yazo zonke iimeko e-Afrika kulo nyaka kunye neepesenti ezingama-97 zokusweleka. Kufanelekile ukuba uqaphele ukuba phantse i-70% yamatyala e-DRC ngabantwana abangaphantsi kweminyaka eli-15s, kwaye eli qela libe ngama-85% okusweleka kweli lizwe.
I-MPOX sisifo sosissis esibangelwa yintsholongwane ye-MPOX ngethuba le-ubume be-5 ukuya kwezingama-21, ubukhulu becala kwiintsuku ezingama-6 ukuya kwezi-13. Umntu owosulelekileyo uya kuba neempawu ezinjengomkhuhlane, intloko ebuhlungu kwaye udumbe i-lymph node, elandelwa yi-rash ebusweni kunye nezinye izinto zomzimba, ngokuthe ngcembe zikhula malunga neveki ngaphambi kokuba isuke. Ityala liyosulela ukuqala kweempawu de kube scabs ziwe ngokwemvelo.
I-Macro kunye ne-Micro-micro ibonelela ngovavanyo olukhawulezileyo, izixhobo ze-molecular kunye nokulandelelana kwezisombululo ze-MPOX, ukubeka esweni intsholongwane ye-MPOX, iliso kwimvelaphi ye-MPOX, imboniselo, ukuhambisa imithombo ye-gemic:
I-Monkeypox intsholongwane i-antignUkufumanisa ikhithi (I-Immunocchirographrographrographrography)
Isampulu elula (isampulu yerhasi / isampulu yomqala) kunye neziphumo ezikhawulezayo ngaphakathi kwe-10-15 imiz;
Ubuntununtunu obuphezulu kunye ne-20pg / ml isigubungelo se-I & II;
Ubunyani obuPhakamileyo obungenamsebenzi-ntsholongwane ngentsholongwane ye-incax, i-variclella ye-ricter, intsholongwane yeRubella yeRubella, i-Harpes Sleenx, njl.
I-OPA ye-96.4% xa ithelekiswa neNaits;
Isicelo ngokubanzi esinje ngamasiko, ii-CDCs, iikhemesti, iikliniki, ezibhedlele okanye ekhaya.
I-Monkeypox-virus Igm / Igg Antiction Kit(I-Ignochromatophy)
Ukusebenza ngokulula kwendlela kunye nokufihlwa kweziphumo ezi-10 min;
Ubuntununtunu obuphezulu kunye nobungqina obugubungele i-I & I & II;
Ichonga i-IGM kunye ne-Igg ukwenza isigqibo se-MPox yosulelo;
Isicelo esibanzi njengamasiko, ii-CDCs, iikhemesti, iikliniki, ezibhedlele okanye ekhaya;
Ilungele ukufunwa okukhulu kosulelo lwe-MPOX.
Ubuntununtunu obuphezulu noPieki we-200 yeekopi / ze-ML nge-IC, ilingana ne-fcr;
Ukusebenza ngokulula: Isampulu ye-LYEDS yongezwa kwi-sugerent ye-fugent ye-fugent ye-Americation ye-Americation ye-Anplication ye-Ambleds yenkqubo ezimeleyo ye-AMP yenkqubo elula;
Ubunyani obuphezulu ngaphandle kokuvela kwentsholongwane yentsholongwane, intsholongwane ye-goninia, intsholongwane ye-Cowpox, intsholongwane ye-Cousepox, intsholongwane ye-vicpos, iVickella-Zoome, njl njl.;
Isampulu elula (i-rash fluid / i-oropharyngeal swab) kunye nesiphumo esikhawulezayo ngaphakathi kwemizuzu emi-5;
I-Toicielical Eclical Eclical Excenting Clade i & I & I-100%, i-NPA ye-100%, i-OPA yexabiso le-100% le-100% ye-1.000 ethelekiswa ne-FCRCR ye-FCR ye-FCR;
I-Liophilvilles Inguqulelo efuna kuphela kuphela izithuthi zothutho kunye nokugcina kusenza ukuba kufikeleleko kuyo yonke imimandla;
Iimeko eziguqukayo kwiiklinikhi, kwiziko lezempilo, kunye ne-AMP elula yokufunyanwa kwasekuqaleni;
I-Monkeypox intsholongwane intsholongwane ye-nucleid ikhithi yokufumanisa (i-fluorescence pcr)
I-Dleedge ejolise kwimvakalelo ephezulu kunye ne-PARE ye-200 yeekopi / ml;
Isampulu eguqukayo ye-rash fluid, umqala swab kunye neserum;
Ubunyani obuphezulu ngaphandle kokuvela kwentsholongwane yentsholongwane, intsholongwane ye-goninia, intsholongwane ye-Cowpox, intsholongwane ye-Cousepox, intsholongwane ye-vicpos, iVickella-Zoome, njl njl.;
Ukusebenza ngokulula: Isampulu ye-Rid Lysis ngu-Itrage ukuqaliswa kwesampulu ukongezwa kwi-tube yokuphendula;
Ukufunyanwa ngokukhawuleza: isiphumo kwisithuba se-40 min;
Ukuchaneka kokuqinisekiswa ngulawulo lwangaphakathi ukongamela inkqubo yonke yokujonga;
I-Tople yeKlinikhi egqwesileyo yeKlinikhi I & I & I & I & NPA ye-99.40%, i-OPA yexabiso le-99.9.64% kunye ne-KAPPA yexabiso le-0.9.33 xa kuthelekiswa nokulandelelana;
I-Liophilvilles Inguqulelo efuna kuphela kuphela izithuthi zothutho kunye nokugcina kusenza ukuba kufikeleleko kuyo yonke imimandla;
Ihambelane ne-fanorescer fluorescence pcc ye-PCR;
Imeko eguqukayo yezibhedlele, ii-CDCs kunye neelebhu;
Intsholongwane ye-Orthopox TOURS TORTAL / Monkeypox intsholongwane ye-nycleic ye-Acid iKit
Ukugubungela ngokupheleleyo: Uvavanyo zonke iintsholongwane ezi-4 ze-Orthopox ezinokusulela umntu kunye ne-MPOX exhaphakileyo (Clade I & I & I & I & I & I & I & I & I & 12) kuvavanyo olunye lokuphepha ukubonwa okuthe kratya;
Ubuntununtunu obuphezulu no-ROPE weekopi ezingama-200 / ml;
Ubungqina obuphezulu ngaphandle kokusebenza kwamanye amantshontsho ebangela i-rassies efana ne-herpes intsholongwane, i-variclella-zester, kunye ne-genome yomntu, njl.;
Ukusebenza ngokulula: Isampulu ye-Rid Lysis ngu-Ispage yesampulu yokuqaliswa ukongezwa kwi-buffer ye-tube enye;
Ukufunyanwa ngokukhawuleza: Ukukhawulezisa ngokukhawuleza okukwi-40 min;
Ukuchaneka kokuqinisekiswa ngulawulo lwangaphakathi ukongamela inkqubo yonke yokujonga;
Ihambelane ne-fanorescer fluorescence pcc ye-PCR;
Imeko eguqukayo yezibhedlele, ii-CDCs kunye neelebhu;
I-MonkeypoxViris TibholaNucleicAi-cidDnxibelelanisaKyona (FI-LuOrescence PCR)
Ngamaxesha athile achonge i-clade i kunye ne-rodi i, ibaluleke kakhulu ekuqondeni iimpawu zentsholongwane, ukulandela amanyathelo athathiweyo, kunye nokulawula amanyathelo ajolise kuyo kunye nolawulo.
Ubuntununtunu obuphezulu no-ROPE weekopi ezingama-200 / ml;
Isampulu eguqukayo ye-rash fluid, i-Oroshfaryngeal Swab kunye neSluum;
Ubuso obuphezulu ngaphandle kokubekwa kwe-Deade phakathi kwe-I kunye ne-I & II, ezinye ii-pathogns ezibangela intsholongwane intsholongwane ye-herpes, i-variclella-zester, njl.;
Ukusebenza ngokulula: Isampulu ye-Rid Lysis ngu-Ispage yesampulu yokuqaliswa ukongezwa kwi-buffer ye-tube enye;
Ukufunyanwa ngokukhawuleza: isiphumo kwisithuba se-40 min;
Ukuchaneka kokuqinisekiswa ngulawulo lwangaphakathi ukongamela inkqubo yonke yokujonga;
I-Liophilvilles Inguqulelo efuna kuphela kuphela izithuthi zothutho kunye nokugcina kusenza ukuba kufikeleleko kuyo yonke imimandla;
Ihambelane ne-fanorescer fluorescence pcc ye-PCR;
Imeko eguqukayo yezibhedlele, ii-CDCs kunye neelebhu;
I-Monkey intsholongwane iphela i-genome yonkeUkuqaphelaIkhithi (I-Multi-PGS)
Intsholongwane esandula ukhulisa i-Monkey ye-genome i-genome yokufumana ikhithi ye-macro kunye ne-Micro-micro yemeko ezahlukeneyo, zidityaniswa ne-ont ye-ont nanopore ilandelelana nge-gexome nganye nge-98% kwiiyure eziyi-98.
Kulula ukusebenza: itekhnoloji yenqanaba elinelungelo lokuziqeqesha, ukulandelelana kwe-genome yonke ye-MPOX virus inokufumaneka ngokukhuliswa ngokujikeleza;
Inovelwano kwaye ichanekile: ifumana iisampulu ezisezantsi ukuya kwi-32ct, kunye ne-600bp ye-Amplilion e-Anopore I-Nanopore Sequening ikwazi ukuhlangabezana neNdibano ye-genome ephezulu.
I-Ultra-Ukukhawuleza: I-ONT inokugcwalisa indibano ye-genome ngeyure ezingama-6-8;
Ukuhambelana ngokubanzi: I-ONT, i-Qi Carbon, Salius Pro, LLLUmina, MGI kunye nolunye fiststream 2ndkunye 3rdabalandeli abanesizukumi.
UbuthathakaI-Monkey Virus iyonke i-genomeUkuqaphelaIkhithi-I-MGumina / MGI(I-Multi-PGS)
Malunga nenani elikhulu le-2ndUkulandelelana kwe-Supener kwihlabathi liphela, iMacro kunye neMicro kunye neMicro kunye ne-Micro-Micro-Cost ikwaphuhlise i-Ultra-Paiting yeKits eqokeleleneyo ukuya kwi-proterical ye-proterest ukufezekisa ukulandelelana kwentsholongwane.
I-amultication efanelekileyo: Iipesenti ezili-1448 ze-200bp ye-Ampplion ye-Amptra-Deperse i-Primer ye-Ander yokusebenza kakuhle kunye nokugubungela iyunifomu;
Ukusebenza ngokulula: I-MPOX VIUS LLUmina / i-MGI Ithala leencwadi elijikeleze iiyure ezimbini kwiiyure ezi-4, ukunqanda amayeza elayibrari athambileyo kunye neendleko zokuqala;
Imvakalelo ephakamileyo: ifumana iisampulu ze-35 ukuya kwi-35CT, ukuphepha iziphumo ezibi ezibangelwa kukonakaliswa kwesiqwengana okanye inombolo yekopi ephantsi;
Ukuhambelana ngokubanzi ne-witstream 2ndAbalandeli abanesizukumi abanjenge-lllmina, i-salus pro okanye mgi;Ukuza kuthi ga ngoku, ngaphezulu kwamatyala ama-400 agqityiwe.
I-Post Time: Aug-28-2024