Rhoqo ngonyaka nge-17 ka-Epreli lusuku lomhlaza wehlabathi.
I-01 yeHlabathi yeHlabathi yeHlabathi yomhlaza
Kwiminyaka yakutshanje, ngokunyuka okuqhubekayo kobomi babantu kunye noxinzelelo lwengqondo, isimo sethumba sikhula unyaka nonyaka.
I-tumugertument (umhlaza) iye yaba yenye yeengxaki eziphambili zempilo yoluntu ezisongela kakhulu impilo yabantu baseTshayina. Ngokwedatha yeenkcukacha-manani zamva nje, ukusweleka kwamalungu angama-23,91% yazo zonke izinto zokufa kwabantu phakathi kwabahlali, kwaye imeko nokufa kwamathumba axhaphakileyo ziye zaphakama kule minyaka ilishumi idlulileyo. Kodwa umhlaza akuthethi ukuba "isigwebo sentambo." Umbutho wezeMpilo weHlabathi chaza ngokucacileyo ukuba lo gama nje ifunyenwe kwangoko, i-60% -90% yomhlaza inokunyangeka! Isinye kwisithathu somhlaza sinokuthintelwa, isinye kwisithathu somhlaza siyanyangeka, kwaye isinye kwisithathu somhlaza sinokunyangwa ukuba sibe nobomi.
02 Yintoni i-tuma
I-tubingetor ibhekisa kwinto entsha eyenziwayo kukwanda kweeseli zezicubu zendawo eziphantsi kwesenzo sezinto ezahlukeneyo ze-tumorigenic. Izifundo ziye zafumanisa ukuba iiseli ze-turus godgo goring utshintsha zahlukile kwiiseli eziqhelekileyo. Kwangelo xesha, iiseli zethumba zinokuziqhelanisa notshintsho kwindawo yeMetabolic ngokuguqula phakathi kwe-GlyColysis kunye ne-phosphory.
I-03 inyanga yomhlaza
Unyango lomhlaza umntu ngamnye lusekwe kulwazi lokuxilongwa kwezifo ekujoliswe kuzo iintlobo kunye neziphumo zophando olusekwe kwezonyango. Inika isiseko sokuba izigulana ukufumana isicwangciso sonyango esifanelekileyo, esiye saba yimfundiso yophuhliso lonyango lwanamhlanje. Izifundo zeklinikhi ziqinisekisile ukuba ngokuguqula i-bimamars, i-gene gene kunye ne-Peerin Proces kwiisampulu ze-bimoos kwizigulo eziqingqiweyo, zinokuphucula ukusebenza kakuhle kwaye zinciphise Ukuphendula, ukukhuthaza ukusetyenziswa kwezixhobo zonyango.
Uvavanyo lwe-molecular lomhlaza lunokwahlulwa kwiindidi ezi-3 eziphambili: Uxilongo, indlalifa kunye nonyango. Uvavanyo lonyango lusezinkozo ezibizwa ngokuba "yi-Perapeutic Pathology" okanye iyeza lomntu, kunye nee-antiboles ezincinci kunye neemolekyuli ezincinci kunye neemoleyitha ezinokuthi zisetyenziswe kunyango lwamathumba.
Imolekyuli ekujoliswe kuyo i-sumurs ijolise kwiimolekyuli ze-tumor yeeseli ze-tumor kwaye zingenelela kwinkqubo yeeseli zomhlaza. Iziphumo zayo ikakhulu kwiiseli ze-tumor, kodwa ineziphumo ezincinci kwiiseli eziqhelekileyo. Izinto zokukhula kwe-tumor, iimolekyuli zoTshintsho, iiproteni ze-Apoptosi, iiProtesi zeProtokoti, zonke izinto zokukhula, njl. Njl. NgoDisemba 28, 2020, "amanyathelo olawulo osetyenziso lweziyobisi ze-antineoplastic (ulingo)" olukhutshwe yiKhomishini yeSizwe kunye neKhomishini yeSizwe ekhutshwa ngokucacileyo ukuba: kwiziyobisi ezicocekileyo zemfuza, ukusetyenziswa kwabo kufuneka kulandelwe emva Ukuvavanywa kwe-genege.
I-04 ye-tumar-ekujoliswe kulonwabo lwemfuzo
Zininzi iindidi zokuguqulwa kofuzo kwizilwanyana, kwaye iintlobo ezahlukeneyo zotshintsho lwendalo zisebenzisa iziyobisi ezahlukeneyo. Ngokukodwa ngokucacisa uhlobo lwe-gene sheet kunye nokukhetha unyango olujolise kwiziyobisi lunokufumana izigulana. Iindlela zokuchonga iimolekyuzi zisetyenziselwa ukufumana ukwahluka kweemfuza ezinxulumene neziyobisi eziqhelekileyo kwi-sumurs. Ngokuhlalutya ifuthe lohlobo lwemfuza ngokusebenza kweziyobisi, sinokunceda oogqirha baphuhlise esona sicwangciso sifanelekileyo sonyango
Isisombululo se-05
Uvavanyo lwe-Macro novavanyo lwe-Macro kunye novavanyo luye lwaqulunqwa uthotho lweekhilomitha zokufunyanwa kwe-turum, ukubonelela ngesicombululo se-tumar esijolise kunyango.
I-ENGR YAMSEBENZI YAMSEBENZI 29 (Fluorescence PCR)
Le khit isetyenziselwa ukuhlolwa kwe-vitro ngokuhambelana notshintsho oluqhelekileyo ekuphakanyisweni kwe-18 ukuya kwi-EGRER kwi-gener kwiisampulu ezivela kwizigulana ezingenamdali.
1. Inkqubo Yazisa Isalathiso sangaphakathi Ulawulo Lwemgangatho, onokuthi ubeke ingqalelo ngokupheleleyo inkqubo yovavanyo kwaye uqinisekise umgangatho wovavanyo.
2. Uvelwano oluphezulu: Ukufunyanwa kwesisombululo sokuphendula nge-nucleic acid kunokukufumanisa ireyithi ye-1% phantsi kwemvelaphi ye-3ng / μl yohlobo lwasendle.
3. Ubungqina obuphezulu: Akukho proces-proctions kunye ne-DNA yohlobo lwe-genomic yomntu kunye nezinye iintlobo zeguquko.
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I-KRASS 8 yokuguqula i-kiking kit (fluorescence pcr)
Le khit yenzelwe ukubongwa kwe-vitro olungeleleneyo kwi-8 yoguquko kwi-codson 12 kunye ne-13 ye-K-Ras Gene kwi-DNA ekhutshiweyo kwiCandelo leParafini.
1. Inkqubo Yazisa Isalathiso sangaphakathi Ulawulo Lwemgangatho, onokuthi ubeke ingqalelo ngokupheleleyo inkqubo yovavanyo kwaye uqinisekise umgangatho wovavanyo.
2. Uvelwano oluphezulu: Ukufunyanwa kwesisombululo sokuphendula nge-nucleic acid kunokukufumanisa ireyithi ye-1% phantsi kwemvelaphi ye-3ng / μl yohlobo lwasendle.
3. Ubungqina obuphezulu: Akukho proces-proctions kunye ne-DNA yohlobo lwe-genomic yomntu kunye nezinye iintlobo zeguquko.
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I-All4-Alk Fusion Strion ye-Ge ye-Gee
Le khiti isetyenziselwa ukufumana i-TREATITITATICECT ye-12 yeentlobo ze-EML4-AlK Fusion kwiisampulu zabantu abangatshatanga zeseli ze-vitro.
1. Inkqubo Yazisa Isalathiso sangaphakathi Ulawulo Lwemgangatho, onokuthi ubeke ingqalelo ngokupheleleyo inkqubo yovavanyo kwaye uqinisekise umgangatho wovavanyo.
2. Imvakalelo ephezulu: Le khit inokufumana utshintsho olusezantsi njengeekopi ezingama-20.
3. Ubungqina obuphezulu: Akukho proces-proctions kunye ne-DNA yohlobo lwe-genomic yomntu kunye nezinye iintlobo zeguquko.
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I-ros ros1 ros1 fusion strion striction ikhutshiwe ikhithi (iFluorescence PCR)
Le khit isetyenziselwa ukubongwa okungangqinelaniyo kweentlobo ezili-14 ze-ros1 ros fusion gene kwiisampulu zomhlaza ezingengaphantsi zeselfowuni.
1. Inkqubo Yazisa Isalathiso sangaphakathi Ulawulo Lwemgangatho, onokuthi ubeke ingqalelo ngokupheleleyo inkqubo yovavanyo kwaye uqinisekise umgangatho wovavanyo.
2. Imvakalelo ephezulu: Le khit inokufumana utshintsho olusezantsi njengeekopi ezingama-20.
3. Ubungqina obuphezulu: Akukho proces-proctions kunye ne-DNA yohlobo lwe-genomic yomntu kunye nezinye iintlobo zeguquko.
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I-Gene v600e ye-Gene v600e yokufumana (i-fluorescence pcr)
Olu khuphiswano lovavanyo luqhele ukuba lenze ngokwenqanaba le-Gene v600e kwisampulu ye-parafini ye-Thelanoma, i-colorecy yomhlaza, umhlaza we-hitroid kunye ne-vitro.
1. Inkqubo Yazisa Isalathiso sangaphakathi Ulawulo Lwemgangatho, onokuthi ubeke ingqalelo ngokupheleleyo inkqubo yovavanyo kwaye uqinisekise umgangatho wovavanyo.
2. Uvelwano oluphezulu: Ukufunyanwa kwesisombululo sokuphendula nge-nucleic acid kunokukufumanisa ireyithi ye-1% phantsi kwemvelaphi ye-3ng / μl yohlobo lwasendle.
3. Ubungqina obuphezulu: Akukho proces-proctions kunye ne-DNA yohlobo lwe-genomic yomntu kunye nezinye iintlobo zeguquko.
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Inombolo yekhathalogu | Igama lemveliso | Ukucaciswa |
I-HWTS-TM012A / B | I-ENGR YAMSEBENZI YAMSEBENZI 29 I-Truoresction Kit (Fluorescence PCR) | Iimvavanyo / ikhithi / iimvavanyo ezingama-32 / ikhithi |
I-HWTS-TM014A / b | I-KRASS 8 yokuguqula i-kiking kit (fluorescence pcr) | Iimvavanyo / ikhithi / iimvavanyo ezingama-48 / kit |
I-HWTS-TM006A / B | I-All4-Alk Fusion Strion ye-Ge ye-Gee | Iimvavanyo / ikhithi / iimvavanyo ezingama-50 / ikhithi |
I-HWTS-TM00999A / B | I-ros ros1 ros1 fusion strion striction ikhutshiwe ikhithi (iFluorescence PCR) | Iimvavanyo / ikhithi / iimvavanyo ezingama-50 / ikhithi |
I-HWTS-TM007A / B | I-Gene v600e ye-Gene v600e yokufumana (i-fluorescence pcr) | Iimvavanyo / ikhithi / iimvavanyo ezingama-48 / kit |
I-HWTS-GE0101 | I-fusion ye-fusion ye-fusion ye-fusion ye-gene | Iimvavanyo ezingama-24 / ikhithi |
Ixesha leposi: APR-17 ukuya ku-923