Itekhnoloji yeMacro kunye neMicro-Test iboniswe kwiNkqubo yokuQala yeSizwe yoHlolo lwe-HPV DNA eNepal evezwe kwi-AMP Europe 2026

I-Macro & Micro-Test iyazingca ngokuba ubuchwepheshe bayo bokuxilonga iimolekyuli ze-HPV busetyenziswe kwinkqubo yokuqala yokuhlolwa komhlaza wesibeleko eNepal esekwe kwi-HPV DNA. Iziphumo zophando zikhethwe kwiNgqungquthela yoMlomo kwi-AMP Europe 2026 Congress kwaye zapapashwa kwiIjenali yokuxilongwa kweMolekyuli, iphephancwadi elisemthethweni le-Association for Molecular Pathology.

Olu phononongo, olukhokelwa yiNational Public Health Laboratory (NPHL) yaseNepal kunye neSebe lezeMpilo kunye noLuntu, luhlalutye abafazi abayi-14,710 kwizithili ezisibhozo, bemele enye yezona nkqubo zinkulu zokuhlola iimolekyuli zeHPV ezenziwe eMzantsi Asia.

Kutheni i-AMP iYurophu ibalulekile

I-AMP Europe yenye yeengqungquthela zamazwe ngamazwe eziphambili ezizinikele ekuxilongweni kweemolekyuli kunye nonyango oluchanekileyo, idibanisa iilabhoratri zeklinikhi, abaphandi, iingcali zezempilo, kunye neengcali zoshishino ezivela kwihlabathi liphela. Iintetho zomlomo zigcinelwe izifundo eziqatshelwa ngabahlaziyi besayensi njengezinexabiso elibalulekileyo kwimpilo yezonyango neyoluntu.

Ukupapashwa kwezishwankathelo zengqungquthela kwiIjenali yokuxilongwa kweMolekyuli(I-Impact Factor: malunga ne-3.7) iphucula ngakumbi ukubonakala kunye nempembelelo yesayensi yezi ziphumo kuluntu lwehlabathi olujongana nokuxilongwa kweemolekyuli.

Iziphumo eziphambili ezivela kwiNkqubo yoHlolo yeSizwe yaseNepal

Inkqubo yokuhlolwa kwesizwe ityhile oku:

• · Abafazi abayi-14,710ihlolwe kusetyenziswa uvavanyo lwe-HPV DNA
• · Ukuxhaphaka kwe-HPV16:1.65%
• · Ukuxhaphaka kwe-HPV18:0.83%
• · Ezinye iintlobo ze-HPV ezinobungozi obukhulu:7.44%
• · I-HPV engekho semngciphekweni ophezulu engekho kwi-16/18Ii-genotypes zibangele uninzi lwezifo.
• · I-HPV ezininzikuchongwe izifo ezihambisanayo, nto leyo egxininisa ukubaluleka kokugutyungelwa kwe-genotype ebanzi kwiindlela zokuhlola kunye nokugonya kwixesha elizayo. 

Ezi ziphumo zibonelela ngobungqina obubalulekileyo be-epidemiological bokuphucula iinkqubo zokuthintela umhlaza wesibeleko eNepal kwaye ziqinisa ukubaluleka kovavanyo olupheleleyo lwe-HPV genotyping ngaphaya kwe-HPV16 kunye ne-HPV18.

Uvavanyo lweMacro kunye nolweMicroI-HPV Enobungozi Obuphezulu Dukuthintela

Inkqubo yokuvavanya yesizwe isebenziseIkhithi yokuFumanisa i-HPV enoMngcipheko oPhezulu kunye novavanyo oluNcinci 14

Iimbalasane zeMveliso

- Iintlobo zeSampulu:Ixhasa zombini iiswabhu zomlomo wesibeleko eziqokelelwe ngoogqirha kunye neesampuli zomchamo, inika ukhetho olulula nolungangenisi ntsholongwane lokuziqokelela ukuphucula ukuthatha inxaxheba ekuhlolweni.

- Ukhuseleko oluBanzi lwe-HPV olunoMngcipheko oPhezulu:Ifumanisa zonke ii-genotypes ze-HPV ezili-14 ezinobungozi obuphezulu eziqatshelwe yi-WHO (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, kunye ne-68). Olu lwazi lupheleleyo lubonisa ukuqondwa okukhulayo kweklinikhi kokuba ii-genotypes ze-HPV ezingezizo eze-16/18 zinegalelo elikhulu kumthwalo womhlaza wesibeleko, ingakumbi kumazwe anengeniso ephantsi nephakathi.

- Uvakalelo oluphezulu lokuHlalutya:Umda wokufumanisaIikopi ezingama-300/mL, okuvumela ukuchongwa okuthembekileyo kosulelo lwe-HPV olunobungozi obuphezulu kwangethuba.

- Ukuhambelana kwePlatform eguquguqukayo:Iyahambelana neenkqubo zePCR zexesha langempela, ivumela ukuhlanganiswa okungenamthungo kwimisebenzi ekhoyo yelebhu.

- Isisombululo seSampuli-ukuya-kwimpendulo esizenzekelayo ngokupheleleyo:Xa idityaniswe neIqonga le-POCT le-Eudemon™ AIO800 elizenzekelayo ngokupheleleyo, olu vavanyo lubonelela ngomsebenzi wokwenyani wesampulu ukuya kwimpendulo kunye nongenelelo oluncinci lomqhubi, lususa ukukhupha i-nucleic acid ngesandla kwaye lwenze lula imisebenzi yelebhu.

Ukuya kwiSicwangciso soKuphelisa uMhlaza weSibeleko se-WHO

Usulelo oluqhubekayo olune-HPV enobungozi obuphezulu luhlala luyimbangela ephambili yomhlaza womlomo wesibeleko—isifo esinokuthintelwa kakhulu ngokuhlolwa ngokufanelekileyo kunye nokungenelela kwangethuba.

I-Macro & Micro-Test isazimisele ekuphuculeni ukuxilongwa kweemolekyuli ezikumgangatho ophezulu kunye nokusebenzisana namaqabane ezempilo kwihlabathi liphela ukuphucula ukufikelela kuvavanyo lwe-HPV oluthembekileyo oluxhasa iinkqubo zesizwe zokuhlola umhlaza wesibeleko.

Sisonke, singakwandisa ukufikelela ekuhlolweni komhlaza wesibeleko size sizise uxilongo lweemolekyuli olusemgangathweni kufutshane nabo bonke abafazi abazidingayo.