01 Yintoni i-GBS?
I-Group B Streptococcus (GBS) yi-Gram-positive streptococcus ehlala kwindlela esezantsi yokugaya ukutya nakwindlela yokuzala yomzimba womntu. Yintsholongwane ebangela amathuba. I-GBS ikakhulu yosulela isibeleko kunye neembrane ze-fetus nge-vagina enyukayo. I-GBS inokubangela usulelo lomchamo lukamama, usulelo lwangaphakathi kwesibeleko, i-bacteremia kunye ne-postpartum endometritis, kwaye yonyusa umngcipheko wokuzala ngaphambi kwexesha okanye ukuzalwa komntwana oswelekileyo.
I-GBS inokubangela ukosuleleka kweentsana ezisandul’ ukuzalwa okanye usana. Malunga ne-10%-30% yabasetyhini abakhulelweyo banesifo se-GBS. Ama-50% ezi zinto anokudluliselwa ngokuthe nkqo kusana olusandul’ ukuzalwa ngexesha lokubeleka ngaphandle kokungenelela, nto leyo ekhokelela kusulelo lweentsana ezisandul’ ukuzalwa.
Ngokwexesha lokuqala kosulelo lwe-GBS, lunokwahlulwa lube ziintlobo ezimbini, olunye luyi-GBS early-onset disease (GBS-EOD), oluvela kwiintsuku ezisi-7 emva kokubeleka, ikakhulu luvela kwiiyure ezili-12-48 emva kokubeleka, kwaye ikakhulu lubonakala njengeBacteremia yosana olusandula ukuzalwa, i-pneumonia, okanye i-meningitis. Olunye luyi-GBS late-onset disease (GBS-LOD), oluvela kwiintsuku ezisi-7 ukuya kwiinyanga ezi-3 emva kokubeleka kwaye lubonakala ikakhulu njenge-bacteremia yosana olusandula ukuzalwa/usana, i-meningitis, i-pneumonia, okanye usulelo lwezitho zomzimba nezitho ezithambileyo.
Ukuhlolwa kwe-GBS ngaphambi kokuzalwa kunye nokungenelela kokubulala iintsholongwane ngaphakathi kokubeletha kunokunciphisa ngempumelelo inani losulelo oluqala kwangoko kwiintsana ezisandula ukuzalwa, kunyuse izinga lokusinda kweentsana ezisandula ukuzalwa kunye nomgangatho wobomi.
02 Ungakuthintela njani?
Ngowama-2010, iZiko loLawulo lweZifo lase-US (i-CDC) laqulunqa "iZikhokelo zoThintelo lwe-GBS yoKubeleka", licebisa ukuba kuhlolwe i-GBS rhoqo kwiiveki ezingama-35-37 zokukhulelwa kwikota yesithathu.
Ngowama-2020, i-American College of Obstetricians and Gynecologists (ACOG) "Consensus on the Prevention of Early-onset Group B Streptococcal Disease in Newborns" icebisa ukuba bonke abafazi abakhulelweyo bafanele bahlolwe i-GBS phakathi kweeveki ezingama-36+0-37+6 zokukhulelwa.
Ngowama-2021, "Imvumelwano yeengcali malunga nokuthintela isifo seStreptococcal seqela B elingaphantsi kokuzalwa (eTshayina)" ekhutshwe liSebe lezonyango elingaphantsi kokuzalwa le-Chinese Medical Association icebisa ukuhlolwa kwe-GBS kubo bonke abafazi abakhulelweyo kwiiveki ezingama-35-37 zokukhulelwa. Icebisa ukuba ukuhlolwa kwe-GBS kusebenze iiveki ezi-5. Kwaye ukuba umntu ongenayo i-GBS akakabeleki iiveki ezingaphezu kwezi-5, kucetyiswa ukuba kuphindwe ukuvavanywa.
Isisombululo se-03
I-Macro & Micro-Test iphuhlise iGroup B Streptococcus Nucleic Acid Detection Kit (Fluorescence PCR), echonga iisampulu ezifana nokuzala komntu kunye nokukhupha i-rectal ukuze kuvavanywe imeko yosulelo lwe-group B streptococcal, kwaye incede abafazi abakhulelweyo ukuba bafumane usulelo lwe-GBS. Le mveliso iqinisekiswe yi-EU CE kunye ne-US FDA, kwaye inomsebenzi ogqwesileyo wemveliso kunye namava amahle omsebenzisi.
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Iingenelo
Okukhawulezileyo: Ukuthatha isampuli okulula, ukukhupha inyathelo elinye, ukufunyanwa ngokukhawuleza
Uvakalelo oluphezulu: i-LoD yekhithi yi-1000 Copies/mL
Iintlobo ezininzi: kuquka iintlobo ezili-12 ezifana ne-la, lb, lc, II, III
I-Anti-ungcoliseko: I-enzyme ye-UNG yongezwa kwinkqubo ukuthintela ngokufanelekileyo ungcoliseko lwe-nucleic acid kwilebhu
| Inombolo yeKhathalogu | Igama lemveliso | Inkcazo |
| I-HWTS-UR027A | Ikhithi yokuFumanisa iStreptococcus Nucleic Acid yeQela B (iFluorescence PCR) | Uvavanyo oluyi-50/ikhithi |
| I-HWTS-UR028A/B | Ikhithi yokuFumanisa iStreptococcus Nucleic Acid yeQela B eyomileyo ngokuqandisa (iFluorescence PCR) | Uvavanyo oluyi-20/ikhithiUvavanyo oluyi-50/ikhithi |
Ixesha lokuthumela: Disemba-15-2022