Umhlaza wemiphunga usengomnye wezona zizathu ziphambili zokufa okubangelwa ngumhlaza kwihlabathi liphela,umhlaza wemiphunga ongengoweeseli ezincinci (i-NSCLC)ukubala okungaphezulu80%kuzo zonke iimeko zomhlaza wemiphunga. Ngo-2020 kuphela, abantu abangaphezu kwe-100Izigidi ezi-2.2Amatyala amatsha omhlaza wemiphunga afunyenwe kwihlabathi liphela

Njengoko i-precision oncology iqhubeka nokutshintsha ulawulo lwe-NSCLC,Uvavanyo lokuguqulwa kwe-EGFR lube sisiseko sonyango oluchanekileyo.Ukuvuselela utshintsho kwii-receptor ye-epidermal growth factor (EGFR)I-gene ziphakathi kwezona biomarkers zisebenzayo kwi-NSCLC, nto leyo evumela ukukhethwa konyango olujoliswe kulo oluphucula kakhulu iziphumo zonyango kwizigulana ezifanelekileyo.

Xa kuthelekiswa ne-chemotherapy eqhelekileyo,Ii-EGFR tyrosine kinase inhibitors (ii-TKI)ukuthintela ngokukhetha iindlela zokubonisa ze-EGFR ezingaqhelekanga eziqhuba ukukhula nokuqhubela phambili kwethumba, zibonelela ngokusebenza ngcono kunye neprofayili yokhuseleko efanelekileyo kwizigulane ezine-NSCLC eguqulwe yi-EGFR. Ukuchonga ngokuchanekileyo nangokufanelekileyo utshintsho lwe-EGFR kubalulekile ekukhetheni unyango lomgca wokuqala olufanelekileyo kunye nokuxhasa izigqibo zonyango ezilandelayo njengoko ukuxhathisa kukhula.

Izikhokelo eziphambili

Izikhokelo zeklinikhi eziphambili zamazwe ngamazwe zihlala zigxininisa ukubaluleka kovavanyo olupheleleyo lwe-biomarker kwizigulane ezine-NSCLC ephucukileyo.

Izikhokelo ze-NCCN Clinical Practice kwi-Oncology

-Cebisa uvavanyo olupheleleyo lweemolekyuli ngaphambi kokuba kuqaliswe unyango olujoliswe kumgca wokuqala kwizigulane ezine-NSCLC ephucukileyo okanye eguqukileyo.

-Imeko yokuguquka kwe-EGFR ibalulekile ekukhetheni unyango olufanelekileyo olujoliswe kulo.

I-ESMO Clinical Practice Guideline

Icebisa uvavanyo oluqhelekileyo lweUtshintsho lwe-EGFR kwi-exons 18–21ukuchonga izigulana ezifanelekileyo kunyango olujoliswe kwi-EGFR.

Ezi ngcebiso zesikhokelo zibonisa indima ebalulekileyo yovavanyo lokuguqulwa kwe-EGFR oluchanekileyo, olunovelwano, nolufike ngexesha elifanelekileyo ekwenzeni unyango oluchanekileyo kwizigulane ezine-NSCLC.

Ikhithi yokuFumanisa utshintsho lwe-EGFR Gene 29 yabantu (i-Fluorescence PCR)-Ukuchonga ngokuchanekileyo kwizigqibo zonyango eziqinisekileyo

Uvavanyo lweMacro kunye nolweMicroIkhithi yokuFumanisa utshintsho lwe-EGFR Gene 29 yabantu (i-Fluorescence PCR)yenza ukuba kubonwe ngokukhawuleza nangokuchanekileyoIinguqu ezingama-29 ezibalulekileyo ze-EGFRngaphesheyaii-exons 18–21, exhasa izigqibo zonyango oluchanekileyo kulo lonke uhambo lwesigulana.

Uvavanyo lubona zombiniutshintsho oluhambelana nokukhuthaza amayeza kunye nokumelana, ukunceda oogqirha bachonge izigulana ezinokungenelwa kunyango olujoliswe kwi-EGFR olufanai-gefitinibkwayei-osimertinib, ngelixa ixhasa ukwenziwa kwezigqibo zonyango kulo lonke ixesha lonyango.

Kutheni Ukhetha Ikhithi Yovavanyo lwe-EGFR yeMacro kunye neMicro-Test?

Ugutyungelwe ngokupheleleyo kotshintsho lwezakhi zofuzo

• · IyafumanisaIinguqu ezingama-29 ze-EGFR ezifanelekileyo ngokwezonyangongaphesheya kwee-exons18–21
• · Igubungela zombiniukukhuthaza ukusetyenziswa kweziyobisikwayeezinxulumene nokuchasanautshintsho
• · Ubuchwepheshe be-ARMS obuphuculweyokunye nesincedisi esinelungelo elilodwa lomenzi ukuze kuqinisekiswe ukuba izinto ezithile ziyasebenza
• · Ukuphucula i-Enzymatickunciphisa imvelaphi ye-wild-type kwaye kuphucula ukuchaneka kokufunyanwa
• · Iteknoloji yokuthintela ubushushukunciphisa ukwandiswa okungafaniyo kwaye kuphucula ukucaca
• · Ifumanisa utshintsho oluvela kwi-I-frequency ye-allele ye-mutant eyi-1%
• · Iziphumo zeenjongo zingadlulanga imizuzu eli-120
• · Ulawulo lwangaphakathi kunyei-enzyme ye-UNGukunciphisa iziphumo ezingezizo ezilungileyo
• · Ixhasa zombiniilaphu, i-plama okanye i-serumii-amples
• · Iyahambelana nezixhobo zePCR zexesha langempela
• · Ixesha lokuphelelwa lixesha leenyanga ezili-12

Itekhnoloji yokuFumanisa ePhambili

Ukusebenza Okuphezulu Kohlalutyo

Ukuhamba komsebenzi okuguquguqukayo

Khokela Unyango Ngokuzithemba

Uvavanyo oluthembekileyo lokuguquka kwe-EGFR luvumela oogqirha ukuba benze izigqibo zonyango ezinolwazi ukususela ekuxilongweni kokuqala ngokubeka esweni ukumelana nezifo.

Uvavanyo olunye. Ugutyungelwe ngokupheleleyo kwenguqu. Ukuzithemba okukhulu ekwenzeni izigqibo zonyango.

Yandisa iPotfoliyo yakho ye-Precision Oncology

I-Macro kunye ne-Micro-Test ikwabonelela ngepotifoliyo epheleleyo yezisombululo zokuxilonga iimolekyuli ze-precision oncology, kuquka: i-KRAS, i-BRAF, i-ROS1, i-ALK, i-BCR-ABL, i-TEL-AML kunye nokunye…

Jonga izisombululo zethu ze-oncology:marketing@mmtest.com