Ngomhla wama-28 kuJulayi 2026, ihlabathi libhiyozelaUsuku lweHlabathi lweHepatitis, iphulo lehlabathi elizinikele ekuphakamiseni ulwazi kunye nokukhawulezisa amanyathelo okulwa ne-hepatitis ebangelwa yintsholongwane. Umxholo walo nyaka uthi,“Isibindi: Masiyihlalutye,”ifuna ukususa imiqobo ethintela ukufikelela ekuthintelweni, ekuvavanyweni, kunyango, nakukhathalelweni kwe-hepatitis.

Njengoko kusele iminyaka engaphantsi kwemihlanu ukufezekisa injongo ye-WHO yokuphelisa i-hepatitis ebangelwa yintsholongwane njengesisongelo kwimpilo yoluntu ngo-2030, ukwandisa ukufikelela kuvavanyo oluchanekileyo nolufikelelwe ngexesha elifanelekileyo akukaze kube yinto ebaluleke kangaka.

Ingozi Engathethiyo: Umthwalo Wehlabathi Lonke We-Hepatitis Ebangelwa Yintsholongwane

I-hepatitis ebangelwa yintsholongwane ibhekisa ekuvuvukeni kwesibindi okubangelwa ziintsholongwane ze-hepatitis, kuqukai-hepatitis A (HAV), B (HBV), C (HCV), D (HDV), kunye ne-E (HEV).

Phakathi kwezi ntsholongwane,i-hepatitis B engapheliyo kunye ne-hepatitis C zihlala zingunobangela oyintloko we-liver cirrhosis kunye ne-hepatocellular carcinoma, idla ngokuqhubeka buthule iminyaka ngaphambi kokuba kuvele iimpawu.

Ngokutsho koqikelelo lwe-WHO, amakhulu ezigidi zabantu kwihlabathi liphela baphila nosulelo olungapheliyo lwe-HBV okanye i-HCV, ngelixa inani elikhulu lingekafunyaniswa. I-hepatitis ebangelwa yintsholongwane iyaqhubeka nokubangela ukufa kwabantu abangaphezu kwesigidi ngonyaka, ikakhulu ngenxa yeengxaki ezifana ne-cirrhosis kunye nomhlaza wesibindi.

Nangona kukho iindlela ezisebenzayo zokuthintela nonyango, izikhewu ekuxilongweni nasekunyamekelweni zisengumngeni omkhulu. Abantu abaninzi abaphila ne-hepatitis engapheliyo abazi ngesifo sabo sosulelo kwaye ngenxa yoko bayaphoswa ngamathuba okungenelela ngexesha elifanelekileyo.

Uvavanyo: Inyathelo Lokuqala Lokuphelisa I-Hepatitis

Ukufezekisa iinjongo zokuphelisa ngo-2030 — kuqukaUkuncipha ngama-90% kwizifo ezintsha ze-hepatitis kunye nokuncipha ngama-65% ekufeni okunxulumene ne-hepatitis— ukwandiswa kwengxelo yovavanyo kubalulekile.

I-WHO igxininisa ukuba ukuphucula ukufikelela ekuxilongweni ngexesha elifanelekileyo kunye nokhathalelo olujoliswe ebantwini kunokuthintela ukufa kwezigidi zabantu. Nangona kunjalo, ukunqongophala kovavanyo oluthembekileyo kusengomnye wemiqobo ephambili ethintela abantu abanesi sifo ekufumaneni unyango olufanelekileyo kunye nokulandelelana.

Njengomboneleli wezinto ezintshaizisombululo zokuxilonga kwi-vitro, Uvavanyo lweMacro kunye nolweMicroizimisele ukuxhasa imizamo yehlabathi yokuphelisa isifo sesibindi ngokusebenzisa ipotifoliyo yovavanyo ebanzi egubungela:

• · Ukuhlolwa ngokukhawuleza ukuze kufunyanwe izinto ezininzi 
• · Uvavanyo lwe-Nucleic acid ukuze kufunyanwe isifo kwangethuba nangokuchanekileyo 
• · Ukubeka iliso kumthwalo wentsholongwane ukuze kulawulwe unyango 
• · Ukuchonga ii-genotyping ukuze kwenziwe izigqibo zeklinikhi ezenzelwe wena 

Ngokuxhasa iimeko ezahlukeneyo zovavanyo, iMacro kunye neMicro-Test zinceda ekwandiseni ukufikelela kuxilongo lwe-hepatitis oluthembekileyo kwihlabathi liphela.

Ipotifoliyo yoVavanyo lweHepatitis yeMacro kunye neMicro-Test

1. Uvavanyo olukhawulezileyo: Ukusondeza uvavanyo lweHepatitis kuluntu

Iikhithi zovavanyo olukhawulezayo lweGolide yeColloidalukubonelela ngesisombululo esilula, esikhawulezayo, nesingenazixhobo, esizisa iziphumo kwimizuzu embalwa. Ezi mvavanyo zifanelekile kwezi:

• · Iinkqubo zokuhlola ezinkulu
• · Iindawo zokhathalelo lwempilo oluphambili
• · Uvavanyo olusekelwe kuluntu
• · Iindawo ezinqongopheleyo kwizixhobo

• Ikati. Hayi.	Igama lemveliso	Uhlobo lweSampuli	Ukusebenza
  I-HWTS-HP011	Ikhithi yokuFumanisa ngokukhawuleza ye-HBsAg (iGolide yeColloidal)	I-serum, iplasma, igazi elipheleleyo	Uvakalelo: 99.53%; Ukuchaneka: 99.67%; I-OPA: 99.63%
  I-HWTS-HP017	Ikhithi yovavanyo olukhawulezayo oludibeneyo lwe-HBsAg kunye ne-HCV Ab (iGolide yeColloidal)	I-serum, iplasma, igazi elipheleleyo	I-HBsAg: IiSens. 99.7%, Inkcazo. 99.8%, I-OPA 99.8%; I-HCV Ab: IiSens. 99.7%, Inkcazo. 99.6%, I-OPA 99.7%
  I-HWTS-HP013	Ikhithi yoVavanyo lwe-HCV Ab (iColloidal Gold)	Igazi elipheleleyo, i-serum, i-plasma	Uvakalelo: 99.39%; Ukuchaneka: 99.81%; I-OPA: 99.71%

• Phakathi kwezi zisombululo,I-HWTS-HP017 ivumela ukufunyanwa ngaxeshanye kwee-antibodies ze-HBsAg kunye ne-HCV kuvavanyo olunye, ukuphucula ukusebenza kakuhle kovavanyo kunye nokuxhasa amaqhinga ovavanyo lwe-hepatitis adibeneyo.
  

  2. Uvavanyo lweNucleic Acid: Ukufumanisa usulelo ngocoselelo

  Uvavanyo lwe-nucleic acid olusekwe kwi-PCR olusebenzisa i-fluorescenceibonelela ngobunono obuphezulu kunye nokuchaneka okunexesha elifutshane, okuvumela ukuchongwa kwangaphambili kwezifo ezibangelwa yintsholongwane kunye nokuxhasa ukwenziwa kwezigqibo zonyango.

• Ikati. Hayi.	Igama lemveliso	Uhlobo lweSampuli	Ukusebenza
  I-HWTS-HP005A	Isixhobo sokuFumanisa i-Hepatitis A Virus Nucleic Acid (i-Fluorescence PCR)	I-serum/isitulo	I-LoD: Iikopi ezingama-500/mL
  I-HWTS-HP001	Isixhobo sokuFumanisa i-Hepatitis B Virus Nucleic Acid (i-Fluorescence PCR)	I-serum	I-LoD: 50 IU/mL
  I-HWTS-HP003	Ikhithi yokuFumanisa i-Hepatitis C Virus RNA Nucleic Acid (i-Fluorescence PCR)	Iplasma/i-serum	50 IU/mL ~ 2×10⁹ IU/mL
  I-HWTS-HP006A	Isixhobo sokuFumanisa i-Hepatitis E Virus Nucleic Acid (i-Fluorescence PCR)	I-serum/isitulo	I-LoD: Iikopi ezingama-500/mL

• 3. Ukulinganiswa koMthwalo weNtsholongwane kunye noHlobo lweJini: Ukuxhasa uLawulo oluchanekileyo

  Kubantu abane-hepatitis B kunye ne-C engapheliyo,Ukubeka iliso kumthwalo wentsholongwane kunye nokuchonga i-genotyping kudlala indima ebalulekileyo kulawulo lwezifo kunye novavanyo lonyango.

   

  Ikati. Hayi.	Igama lemveliso	Uhlobo lweSampuli	Ukusebenza
  I-HWTS-HP015	Isixhobo sokuxilonga i-Hepatitis B Virus DNA Quantitative Fluorescence Diagnostic Kit (i-Fluorescence PCR)	I-serum/iplasma	Uluhlu lobungakanani: 20 IU/mL ~ 2×10⁹ IU/mL
  I-HWTS-HP002	Isixhobo sokuFumanisa iiGenotyping zeHepatitis B Virus (iFluorescence PCR)	I-serum/iplasma	I-LoD: 1 × 10² IU/mL
  I-HWTS-HP004	Ikhithi yokuFumanisa iGenotyping ye-HCV (i-Fluorescence PCR)	I-serum/iplasma	I-LoD: 200 IU/mL

• I-HBV inee-genotypes ezininzi (A–I), ezinokuchaphazela iimpawu zentsholongwane kunye nolawulo lweklinikhi.I-HWTS-HP002 kunye ne-HWTS-HP004 zibonelela ngolwazi lwe-genotyping ukuxhasa amaqhinga onyango anolwazi oluthe kratya, ngelixaI-HWTS-HP015 inika uluhlu olubanzi lokulinganisa ukujonga amandla entsholongwane kulo lonke uhambo lonyango. 
  

  Ukunika amandla ikamva elingena-Hepatitis ngokuxilongwa ngokuchanekileyo

  I-hepatitis yentsholongwaneinokuthintelwa, iyalawuleka, kwaye — kwimeko ye-hepatitis C — iyanyangeka.

  • · I-Hepatitis Binokuthintelwa ngempumelelo ngokugonywa kwaye ilawulwe ngolawulo olufanelekileyo lwee-antiviral.
  • · I-Hepatitis Cinokunyangeka ngonyango olusebenza ngqo kwiintsholongwane, nto leyo efikelela kumanqanaba okuphiliswa angaphezu kwama-95%.

  Nangona kunjalo, inyathelo lokuqala lihlala lifana:ukuchonga izifo kwangethuba ngovavanyo oluthembekileyo.

Ukususela ekuhlolweni ngokukhawuleza ukuya ekufumaneni iimolekyuli, ukusuka ekuxilongweni okusemgangathweni ukuya ekubekweni kweliso lomthwalo wentsholongwane kunye nokuchonga i-genotyping,I-Macro & Micro-Test ibonelela ngepotifoliyo epheleleyo yovavanyo lwe-hepatitis egubungela i-hepatitis A, B, C, kunye ne-E — enceda ekuqhekezeni imiqobo yokuxilonga kunye nokuxhasa imizamo yehlabathi yokuphelisa i-hepatitis.

NgoSuku lweHlabathi lweHepatitis luka-2026, masisebenzisane ukuze“yidilize” — ukudiliza imiqobo, ukwandisa ukufikelela, kunye nokukhawulezisa inkqubela phambili eya kwikamva elingenasifo sesibindi.