Umxholo wethumba
I-tumar yinto entsha yento ephilayo ngokunyanzeliswa kweeseli zemizimba emzimbeni, ehlala ibonisa ukuba i-tous engaqhelekanga (intlama) kwinxalenye yendawo yomzimba. Ukuqulunqwa kwe-tumor sisiphumo sokungakhathali okukhulu kommiselo wokukhula kweseli phantsi kwesenzo sezinto ezahlukeneyo ze-tumorigedic. Ukuqhutywa okungaqhelekanga kweeseli ezikhokelela kwi-tumor ye-tumor kubizwa ngokuba yi-neolistic.
Ngo-2019, iseli yomhlaza ipapashwe inqaku kutshanje. Abaphandi bafumanise ukuba i-metformin ingayithintela kakhulu ukukhula kwe-tumor kwimeko yokuzila, kwaye iphakamise ukuba i-PP2A-GSK3-TSK-MCL-1 yendlela inokuba yithagethi entsha yonyango.
Umahluko ophambili phakathi kwe-Bign Tumor kunye ne-tumagent tumament
I-Begn Tumor: Ukukhula kancinci, i-capsule, ukukhula kokudumba, ukuhambisa umda, akukho mda mhle, akukho mzimba ulungileyo, ingekho mzimba iphela, ihlala ingenzi ukuba ifa sisigulana.
I-tumant tumar (umhlaza): Ukukhula ngokukhawuleza, ukukhula okungahlaseli, ukunamathela kwizicubu ezijikelezileyo, i-fives elula, ukunciphisa umzimba, ukunciphisa umzimba, ukunciphisa umzimba, I-ANAMIA kunye ne-fever kwinqanaba lokugqibela, njl njl. Ukuba ayiphathwa ngexesha, ihlala ikhokelela ekufeni.
"Kungenxa yokuba amathumba e-Bign kunye namathumba amnandi awabinalo nje ukubonakaliswa kweklinikhi, kodwa okona kubaluleke kakhulu, ukusikwa kwabo kwahlukile, xa sele ufumana intlama emzimbeni wakho kunye nale mpawu zingasentla, kufuneka ufumane iingcebiso zezonyango ngexesha.
Unyango lomntu ngamnye
IProjekthi yeGenome yomntu kunye neProjekthi yoMhlaza weHlabathi yeHlabathi
Iprojekthi ye-genome yomntu, eye yasungulwa ngokusemthethweni e-United States ngo-1990, ijolise ekuvuneni zonke iikhowudi ezinokubakho malunga ne-100,000 yemfuza emzimbeni womntu kwaye uzobe imbonakalo yemfuza yomntu.
Ngo-2006, iprojekthi yomhlaza wamazwe onke, ehlelwe ngokudibeneyo kumazwe amaninzi, lolunye uphando olukhulu lwezenzululwazi emva kweprojekthi ye-genome yomntu.
Iingxaki eziphambili kunyango lwethumba
Ukuxilongwa komntu ngamnye kunye nonyango = isifo sokufumanisa umntu +
Kwizigulana ezahlukeneyo ezibandezeleka kwisifo esinye, indlela yonyango kukusebenzisa iyeza elifanayo kunye nedosi eliqhelekileyo, kodwa, enyanisweni, iigulana ezahlukeneyo zinezinto ezikhoyo kunyango kwaye ngamanye amaxesha kuya kufana nolwahlulo.
Unyango olujolise lweziyobisi luneempawu zokubulawa kweeseli ze-tumor ngaphandle kokubulala okanye zibize intshabalalo eyonakalisiyo, kunye neziphumo ezibi kakhulu, eziphucula umgangatho wobomi kunye nefuthe lonyango lwezigulana.
Ngenxa yokuba unyango olujolisiweyo lwenzelwe ukuhlasela iimolekyuli ezijolise kuzo, kuyimfuneko ukufumana i-sumor ye-turus kwaye ibone ukuba izigulana zijolise ekusebenziseni iziyobisi, ukuze zisebenzise isiphumo sayo.
Ukufunyanwa kwe-turu
Ukufunyanwa kwe-sumor gene yindlela yokuhlalutya kwaye ulandele i-DNA / RNA yeeseli ze-tumor.
Ukubaluleka kokufunyanwa kwe-turus gene kukukhokela ekukhetheni ichiza lonyango lweziyobisi (iziyobisi ekujoliswe kuzo, i-ofisi yendawo yokutshekisha, kunye nezinye izinto ezintsha, kunye nokuqiqa.
Izisombululo ezibonelelwe yi-ACT Macro & Micro-Micro-Micro-Micro
Isetyenziselwa ukubongolwa okuqhelekileyo kotshintsho oluqhelekileyo kwi-18 ukuya kwi-ENGR KEFRE kwizigulana zomhlaza ezingenamdanga ze-vitro.
1. Ukwaziswa kwesalathiso sangaphakathi Ukulawulwa komgangatho wolawulo lwangaphakathi kwinkqubo kunokukuqinisekisa ngokupheleleyo inkqubo yovavanyo kwaye uqiniseke ukuba umgangatho wovavanyo.
2. Imvakalelo ephezulu: Ixabiso lokuTshintsha le-1% linokufunyanwa nge-3ng / μl yohlobo lwe-nucleid ye-nucleid ye-asidi.
3. Ubungqina obuphezulu: Akukho nto inqamlezayo kunye nokufunyanwa kweziphumo zeDNA ye-DNA ye-gemic yomntu yasendle kunye nezinye iintlobo zeguquko.
I-KRASS 8 yokuguqula i-kiking kit (fluorescence pcr)
Iintlobo ezisibhozo zokuguquguquka kwi-codson 12 ne-13 ye-K-Ras Geene esetyenzisiweyo yokufunyanwa kwe-DNA ekhutshwe kwicandelo leParafini-ye-vitro.
1. Ukwaziswa kwesalathiso sangaphakathi Ukulawulwa komgangatho wolawulo lwangaphakathi kwinkqubo kunokukuqinisekisa ngokupheleleyo inkqubo yovavanyo kwaye uqiniseke ukuba umgangatho wovavanyo.
2. Imvakalelo ephezulu: Ixabiso lokuTshintsha le-1% linokufunyanwa nge-3ng / μl yohlobo lwe-nucleid ye-nucleid ye-asidi.
3. Ubungqina obuphezulu: Akukho nto inqamlezayo kunye nokufunyanwa kweziphumo zeDNA ye-DNA ye-gemic yomntu yasendle kunye nezinye iintlobo zeguquko.
I-ros ros1 ros1 fusion strion striction ikhutshiwe ikhithi (iFluorescence PCR)
Isetyenziselwa ukufumana ngokufanelekileyo iinguqu ezi-14 ze-ros1 fusion gene kwizigulana zomhlaza ezingengaphantsi ze-vitro.
1. Ukwaziswa kwesalathiso sangaphakathi Ukulawulwa komgangatho wolawulo lwangaphakathi kwinkqubo kunokukuqinisekisa ngokupheleleyo inkqubo yovavanyo kwaye uqiniseke ukuba umgangatho wovavanyo.
2. Imvakalelo ephezulu: 20 Iikopi zokuguquguquka kwembumbulu.
3. Ubungqina obuphezulu: Akukho nto inqamlezayo kunye nokufunyanwa kweziphumo zeDNA ye-DNA ye-gemic yomntu yasendle kunye nezinye iintlobo zeguquko.
I-All4-Alk Fusion Strion ye-Ge ye-Gee
Isetyenziselwa ukufumana ngokufanelekileyo iinguqu ezi-12 ze-Eml4-Alk Fusion kwizigulana zomhlaza ezingengaphantsi ze-vitro.
1. Ukwaziswa kwesalathiso sangaphakathi Ukulawulwa komgangatho wolawulo lwangaphakathi kwinkqubo kunokukuqinisekisa ngokupheleleyo inkqubo yovavanyo kwaye uqiniseke ukuba umgangatho wovavanyo.
2. Imvakalelo ephezulu: 20 Iikopi zokuguquguquka kwembumbulu.
3. Ubungqina obuphezulu: Akukho nto inqamlezayo kunye nokufunyanwa kweziphumo zeDNA ye-DNA ye-gemic yomntu yasendle kunye nezinye iintlobo zeguquko.
I-Gene v600e ye-Gene v600e yokufumana (i-fluorescence pcr)
Isetyenziselwa ukufumana impilo yokuguqula i-Braf Gene v600e kwisampulu ye-thematofini ye-Thelanoma, i-colorecy yomhlaza, umhlaza we-hitroid kunye ne-vitro.
1. Ukwaziswa kwesalathiso sangaphakathi Ukulawulwa komgangatho wolawulo lwangaphakathi kwinkqubo kunokukuqinisekisa ngokupheleleyo inkqubo yovavanyo kwaye uqiniseke ukuba umgangatho wovavanyo.
2. Imvakalelo ephezulu: Ixabiso lokuTshintsha le-1% linokufunyanwa nge-3ng / μl yohlobo lwe-nucleid ye-nucleid ye-asidi.
3. Ubungqina obuphezulu: Akukho nto inqamlezayo kunye nokufunyanwa kweziphumo zeDNA ye-DNA ye-gemic yomntu yasendle kunye nezinye iintlobo zeguquko.
| Into | Igama lemveliso | Ukucaciswa |
| I-HWTS-TM006 | I-All4-Alk Fusion Strion ye-Ge ye-Gee | Iimvavanyo ezingama-20 / ikhithi Iimvavanyo ezingama-50 / ikhithi |
| I-HWTS-TM007 | I-Gene v600e ye-Gene v600e yokufumana (i-fluorescence pcr) | Iimvavanyo ezingama-24 / ikhithi Iimvavanyo / ikhithi |
| I-HWTS-TM009 | I-ros ros1 ros1 fusion strion striction ikhutshiwe ikhithi (iFluorescence PCR) | Iimvavanyo ezingama-20 / ikhithi Iimvavanyo ezingama-50 / ikhithi |
| I-HWTS-TM012 | I-ENGR YAMSEBENZI YOBUGCISA) | Iimvavanyo ezili-16 / ikhithi Iimvavanyo ezingama-32 / ikhiti |
| I-HWTS-TM014 | I-KRASS 8 yokuguqula i-kiking kit (fluorescence pcr) | Iimvavanyo ezingama-24 / ikhithi Iimvavanyo / ikhithi |
| I-HWTS-TM016 | I-Am-Aml1 yeTl-Aml1 fusion ye-Gee | Iimvavanyo ezingama-24 / ikhithi |
| I-HWTS-ge010 | I-fusion ye-fusion ye-fusion ye-fusion ye-gene | Iimvavanyo ezingama-24 / ikhithi |
IXESHA LOKUQALA: APR-17 ukuya ku-924