IZaire eyomileyo eqandisiweyo kunye neSudan Ebolavirus Nucleic Acid

I-Ebolavirus yeyeFiloviridae, eyintsholongwane yeRNA enemicu engenanto ingenazicucu. Iintsholongwane ziifilaments ezinde ezinobude obuphakathi be-virion obuyi-1000nm kunye nobubanzi obuyi-100nm. I-genome ye-Ebolavirus yi-RNA enemicu engenanto ingenazicucu enobukhulu be-18.9kb, equlethe iiproteni ezisi-7 zesakhiwo kunye neproteni enye engeyiyo yesakhiwo. I-Ebolavirus inokwahlulwa ibe ziintlobo ezifana neZaire, Sudan, Bundibugyo, Tai Forest kunye neReston. Phakathi kwazo, uhlobo lweZaire kunye nohlobo lweSudan kuye kwaxelwa ukuba zibangela ukufa kwabantu abaninzi ngenxa yosulelo. I-EHF (Ebola Hemorrhagic Fever) sisifo esosulelayo esosulelayo esibangelwa yi-Ebolavirus. Abantu bosulelwa kakhulu kukudibana nolwelo lomzimba, ukukhupha kunye nendle yezigulana okanye izilwanyana ezosulelekileyo, kwaye iimpawu zeklinikhi ikakhulu ngumkhuhlane ophumayo, ukopha kunye nomonakalo wamalungu amaninzi. I-EHF inezinga eliphezulu lokufa eliyi-50%-90%. Okwangoku, iindlela zokuchonga i-Ebolavirus ikakhulu ziimvavanyo zelebhu, kuquka iinkalo ezimbini: ukufumanisa i-etiological kunye nokufumanisa i-serological. Ukufumanisa i-etiological kuquka ukufumanisa ii-antigens zentsholongwane kwiisampuli zegazi nge-ELISA, ukufumanisa ii-nucleic acids ngeendlela zokukhulisa ezifana ne-RT-PCR, njl., kunye nokusebenzisa iiseli i-Vero, i-Hela, njl. ukuze kwahlulwe iintsholongwane kwaye kukhuliswe intsholongwane. Ukufumanisa i-serological kuquka ukufumanisa ii-antibodies ezithile ze-Serum IgM ngokubamba i-ELISA, kunye nokufumanisa ii-antibodies ezithile ze-Serum IgG nge-ELISA, i-immunofluorescence, njl.