I-tel-aml1 ye-aml1 fusion swion
Igama lemveliso
I-HWTS-TM016 yoMntu weTel-Aml1 fusion swion ye-Gee
Isipikumu
I-abute lymphoblastic leukemia (yonke) yeyona nto ixhaphakileyo ebuntwaneni. Kwiminyaka yakutshanje, i-Acutemia (Al) itshintshiwe kwi-MIC (Morphology, i-Iytology, i-cytogonetics) ukuya kuvavanyo lwe-moleclor). Ngo-1994, kwafunyaniswa ukuba ukufuduswa kwetel ebuntwaneni yabangelwa kukudluliselwa kwe-norbrandom chrondom ye-T (12; 21). Ukususela ekufumanekeni kwe-Aml1 Fusion, i-Aml-Aml1 fusion yeyona ndlela ilungileyo yokugweba i-progenosis yabantwana abanobunzima i-luphuclablaftia.
Ijelo
| Indlala | I-Tel-Aml1 vesion phes |
| Rox | Ulawulo lwangaphakathi |
Iiparamitha zobugcisa
| Ukugcinwa | ≤-18 ℃ |
| Beka ubomi kwishelufa | Iinyanga ezili-9 |
| Uhlobo locaphu | isampulu ye-bone |
| Ct | ≤40 |
| CV | <5.0% |
| Indawo yokuhlala | I-1000copies / ml |
| Ubuchule | Akukho sithuba sokuhlakulela phakathi kweekhithi kunye nezinye iimfusi ezifana ne-BCR-ABL, E2A-PBX1, ML-AF4, AML1-EAML-TO, PML-RORA fusion ges. |
| Izixhobo ezifanelekileyo | Faka isicelo se-biosystemsts 700 ye-PCR ye-PCR ye-PCR Faka isicelo se-biosystemsts ezingama-700 ngokukhawuleza kwe-PCR ye-PCR I-CARTUDIONIO®5 I-PAY-Time-Times Spish Spish I-Slan-96p yangempela ye-PCR ye-PCR I-FIMCYCLER ®480 ye-PALCR ye-PCR ye-PCR I-Linegene 9600 kunye neNkqubo yokufumana iPRRR Ma-6000 ubungakanani bexesha lokwenyani I-biorad cfx96 yeyokwenyani ye-PFRR I-biorad cfx opi 96 Inkqubo ye-PFR ye-PCR |
Ukuhamba komsebenzi
RNaprep Igazi eliQinisekileyo i-RNA Commiction Kit (DP433).
