I-cyp2c ye-cyp2c19 yemfuza yemfuza

Inkcazo emfutshane:

Le khit isetyenziselwa ukubongwa kwe-vitrom ye-vitrorphism ye-pyp2c19 i-cyp2c19 * 2 (R4342G> A), i-CYP2C19 * 17 (R12285), C.806 > T) kwiDNA ye-gemic kwiisampulu zegazi lomntu.


Iinkcukacha zemveliso

Iimpawu zeMveliso

Igama lemveliso

I-HWTS-GE012A-I-CYP2C yomntu ye-cyp2c19 ye-Gene Polymorphism

Isatifiketi

I-CE / TFDA

Isipikumu

I-cyp2c19 yenye yeyona nto ibalulekileyo ye-enazymes ye-enzymes yosapho kwi-cyp450. Uninzi lwamantshontsho e-Endogenous kwaye malunga ne-2% yamachiza ekliniki afakwe i-Cyp2c19, efana ne-metabolism ye-antipares (i-protozogrebrel), i-proton polymorphism ikwanokwahluka kwe inxulumene iziyobisi. Ezi zinto ziguqukayo ze-2 (i-RS424285) kunye * 3 (R4986893) Yiba nobuthathaka be-Enzyme Deaged ye-Cyp2c uxinzelelo lwegazi. * 17 (I-Rs12248560) inokunyusa umsebenzi we-enzyme odityanisiweyo nge-cyp2c19, ukuveliswa kweemetare zeMetali, kunye nokwandisa umngcipheko wobumbeko. Kubantu abanee-metabolism ezicothayo, bethatha iidosi eziqhelekileyo ixesha elide baya kubangela ityhefu yetyhefu yetyhefu yetyhefu yetyhefu, i-Hematopoit Mores, i-Hematopoiet System, inokuthi ikhokele ekufeni kwamatyala anzima. Ngokutsho komehluko ngamnye kwimetabolism ehambelanayo, oko kukuqhekeziwe ngamagama amane e-metabolism (I-UM, * 17 / * 17, * 1 / * 1 ), I-metabolism ephakathi (im, * 1 / * 2, * 1 / * 3), i-Trayitha icothayo (pm, * 2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2/2 / * 2, * 3 / * 3).

Ijelo

Indlala I-cyp2c19 * 2
I-Cy5 I-cyp2c9 * 3
Rox I-cyp2c19 * 17
I-vic / hex IC

Iiparamitha zobugcisa

Ukugcinwa Ulwelo: ≤-18 ℃
Beka ubomi kwishelufa Iinyanga ezili-12
Uhlobo locaphu Igazi elitsha lase-Edta i-anticoed
CV ≤5.0%
Indawo yokuhlala 1.0ng / μl
Ubuchule Akukho candelo lokungavisisani kunye nolunye ulandelelwano oluguqukayo (i-cyp2c9 gene) kwi-genome yomntu. Ukuguquguquka kwe-cyp2c19 * 23, I-23, i-cyp2c19 * 24 kunye ne-24 kunye ne-cyp2c19 * I-Syp2c19 * I-SCP2C19 * Iisayithi ezingama-25 ezingafunekiyo Akukho mpembelelo kwi-Kit.
Izixhobo ezifanelekileyo Faka isicelo se-biosystemsts 700 ye-PCR ye-PCR ye-PCR

Faka isicelo se-biosystemsts ezingama-700 ngokukhawuleza kwe-PCR ye-PCR

I-CARTUDIONIO®5 I-PAY-Time-Times Spish Spish

I-Slan-96p yangempela ye-PCR ye-PCR

I-FIMCYCLER ®480 ye-PALCR ye-PCR ye-PCR

I-Linegene 9600 kunye neNkqubo yokufumana iPRRR

Ma-6000 ubungakanani bexesha lokwenyani

I-biorad cfx96 yeyokwenyani ye-PFRR

I-biorad cfx opi 96 Inkqubo ye-PFR ye-PCR

Ukuhamba komsebenzi

Ukucetyiswa Ukuqulunqwa kwe-Reagent: I-Macro kunye ne-Macro kunye ne-RNA Kit (HWTS-3019) Co., Ltd. Ukukhutshwa kufuneka kukhutshwe ngokwemiyalelo. Ithamsaneli yesampulu ye-STOSY, kunye nevolumu ye-Elpress i-100μl.

Ukucetyiswa ukwenziwa kwe-Rement: I-Wizard ® i-DNA yokucoca i-DNA Ikhithi (ikhathalogu hayi. kufuneka ikhutshwe ngokwemiyalelo yokukhutshelwa, kunye nevolumu yokukhuphela i-200 μl kunye nevolumu ye-Elpress ecetyiswayo yi-160 μl.


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