I-Human Papillomavirus (HPV) yeyosapho lwe-Papillomaviridae ye-molecule encinci, engaguqukiyo, ejikelezayo, i-virus ye-DNA enemisonto ephindwe kabini, kunye nobude be-genome malunga ne-8000 ye-base pairs (bp).I-HPV yosulela abantu ngokudibana ngokuthe ngqo okanye ngokungathanga ngqo nezinto ezisulelekileyo okanye usulelo lwesondo.Intsholongwane ayikho kuphela i-host-specific, kodwa i-tissue-specific, kwaye inokosulela kuphela ulusu lomntu kunye neeseli ze-epithelial ze-mucosal, ezibangela iindidi ze-papillomas okanye iintsumpa eluswini lomntu kunye nomonakalo okhulayo kwi-epithelium yendlela yokuzala.
Ikhithi ifanelekile kwi-in vitro qualitative typing typing ye-14 iintlobo ze-human papillomaviruses (HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68) nucleic acids iisampulu zomchamo womntu, iisampulu zeswabhu yomlomo wesibeleko yabasetyhini, kunye neesampulu zeswabhu yelungu lobufazi.Inokubonelela kuphela ngeendlela ezincedisayo zokuxilongwa kunye nonyango losulelo lwe-HPV.